Novel central dopaminergic agents derived from atypical di-substituted 2-aminoindane-4, 7. Synthesis and central pharmacological profile

In recent decades, many compounds with central dopaminergic activity have been designed, synthesized and evaluated pharmacologically. However, it has not been possible to obtain a drug able to improve or cure diseases involving dopaminergic regulation in the central nervous system, such as Parkinson...

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Veröffentlicht in:	Investigación clínica 2015-06, Vol.56 (2), p.137-154
Hauptverfasser:	Ferrer-Mavárez, Rosa Elena, Urdaneta-Gutierrez, Noribel Coromoto, Porta-Knabenschuh, Nicole, Rodríguez-Villasmil, Lucía Chiquinquirá, Rosales-Peña, Cecire Carolina, Espinoza, Gustavo Adolfo, Angel-Migliore, Ligia Biagina, Balza-Jiménez, Katherin del Carmen, Perdomo-Zavarce, Luis Eduardo, Faría-Quintero, Andrés Rafael, Dabian-Makarem, Akram Samear, Zapata-Cárdenas, Mariana Vanessa, Linero-Arrieta, Aarón Raúl, Acurero-Castellano, Gustavo Adolfo, Israel-Stern, Anita, Rosario Garrido, María, Suárez-Roca, Heberto, Migliore de Angel, Biagina del Carmen, Lopez-D'Sola, Simón Enrique, Charris-Charris, Jaime, Ramírez-Moran, María Matilde, Angel-Guío, Jorge Eduardo
Format:	Artikel
Sprache:	spa
Schlagworte:	Animals Behavior, Animal - drug effects Dopamine Agonists - chemical synthesis Dopamine Agonists - chemistry Dopamine Agonists - pharmacology Dopamine Antagonists - chemical synthesis Dopamine Antagonists - chemistry Dopamine Antagonists - pharmacology Indans - chemical synthesis Indans - chemistry Indans - pharmacology Injections, Intraventricular Male Rats Rats, Sprague-Dawley Stereotyped Behavior - drug effects Structure-Activity Relationship
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