Long-term survivors with continuously high levels of HIV type 1

HIV infection usually leads to a gradual loss of CD4-positive lymphocytes, declining immune functions, and a concomitant increase in HIV-1 levels. Among long-term survivors CD4-positive T lymphocyte numbers remain at near normal levels for many years, while HIV-1 loads remain relatively low. We repo...

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Veröffentlicht in:AIDS research and human retroviruses 1996-06, Vol.12 (9), p.757-758
Hauptverfasser: Rump, J A, Peter, H H, Schneider, J, Haller, O, Meyerhans, A
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container_issue 9
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creator Rump, J A
Peter, H H
Schneider, J
Haller, O
Meyerhans, A
description HIV infection usually leads to a gradual loss of CD4-positive lymphocytes, declining immune functions, and a concomitant increase in HIV-1 levels. Among long-term survivors CD4-positive T lymphocyte numbers remain at near normal levels for many years, while HIV-1 loads remain relatively low. We report here an unusual combination of stable CD4-positive lymphocyte levels accompanied by elevated virus loads in two long-term seropositive individuals.
doi_str_mv 10.1089/aid.1996.12.757
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identifier ISSN: 0889-2229
ispartof AIDS research and human retroviruses, 1996-06, Vol.12 (9), p.757-758
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source Mary Ann Liebert Online Subscription; MEDLINE
subjects Adult
Carrier State - immunology
CD4 Lymphocyte Count
Cytopathogenic Effect, Viral
HIV Infections - immunology
HIV-1 - immunology
HIV-1 - physiology
human immunodeficiency virus 1
Humans
Immunocompetence
Male
Middle Aged
Survivors
title Long-term survivors with continuously high levels of HIV type 1
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