Improving perfusion quantification in arterial spin labeling for delayed arrival times by using optimized acquisition schemes

The improvement in Arterial Spin Labeling (ASL) perfusion quantification, especially for delayed bolus arrival times (BAT), with an acquisition redistribution scheme mitigating the T1 decay of the label in multi-TI ASL measurements is investigated. A multi inflow time (TI) 3D-GRASE sequence is prese...

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Veröffentlicht in:	Zeitschrift für medizinische Physik 2015-09, Vol.25 (3), p.221-229
Hauptverfasser:	Kramme, Johanna, Gregori, Johannes, Diehl, Volker, Madai, Vince I., von Samson-Himmelstjerna, Federico C., Lentschig, Markus, Sobesky, Jan, Günther, Matthias
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Algorithms Arterial Spin Labeling ASL Blood Flow Velocity bolus arrival time Bolus-Ankunftszeit Carotid Stenosis - diagnosis Carotid Stenosis - physiopathology Computer Simulation Contrast Media - pharmacokinetics Female Humans Image Enhancement - methods Image Interpretation, Computer-Assisted - methods Magnetic Resonance Angiography - methods Magnetic Resonance Imaging Magnetresonanz-Bildgebung Male Middle Aged Models, Cardiovascular optimierte Bildaufnahme optimized acquisition perfusion Reproducibility of Results Sensitivity and Specificity signal to noise Signal zu Rauschen Spin Labels
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