Sub-optimal responders following controlled ovarian stimulation: an overlooked group?
Individualization of IVF treatment and tailored stimulation based on predicted ovarian response may maximize treatment success and minimize the risks following IVF. Whilst there has been a consensus in defining poor ovarian response and an attempt to elucidate the threshold for excessive ovarian res...
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Veröffentlicht in: | Human reproduction (Oxford) 2015-09, Vol.30 (9), p.2005-2008 |
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container_end_page | 2008 |
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container_issue | 9 |
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container_title | Human reproduction (Oxford) |
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creator | Polyzos, N.P. Sunkara, S.K. |
description | Individualization of IVF treatment and tailored stimulation based on predicted ovarian response may maximize treatment success and minimize the risks following IVF. Whilst there has been a consensus in defining poor ovarian response and an attempt to elucidate the threshold for excessive ovarian response based on the number of oocytes retrieved following ovarian stimulation, no systematic effort has been made in order to refine the oocyte yield thresholds for a normal responder. In this opinion article we discuss the evidence behind the oocyte number thresholds for the ovarian response categories and present the rationale and merits in recognizing a new, overlooked, ovarian response group: The sub-optimal ovarian responders. |
doi_str_mv | 10.1093/humrep/dev149 |
format | Article |
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Whilst there has been a consensus in defining poor ovarian response and an attempt to elucidate the threshold for excessive ovarian response based on the number of oocytes retrieved following ovarian stimulation, no systematic effort has been made in order to refine the oocyte yield thresholds for a normal responder. 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In this opinion article we discuss the evidence behind the oocyte number thresholds for the ovarian response categories and present the rationale and merits in recognizing a new, overlooked, ovarian response group: The sub-optimal ovarian responders.</description><subject>Adult</subject><subject>Cell Count</subject><subject>Evidence-Based Medicine</subject><subject>Female</subject><subject>Humans</subject><subject>Oocytes</subject><subject>Ovulation Induction</subject><subject>Reference Values</subject><subject>Treatment Outcome</subject><issn>0268-1161</issn><issn>1460-2350</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkL1PwzAQxS0EoqUwsqKMLKH-iJ2EBaGKL6kSA3SOHOdSAk4c7DiI_x6jFBiZ7p7007t7D6FTgi8IztnyxbcW-mUFI0nyPTQnicAxZRzvozmmIosJEWSGjpx7xTismThEMyoopjyjc7R58mVs-qFppY4suN50FVgX1UZr89F020iZbrBBQRWZUdpGdpELuNdyaEx3GQVtRrDamLeAbK3x_dUxOqildnCymwu0ub15Xt3H68e7h9X1OlZM8CEWlMsU04ykUJKSkYzl4ccqUZDXOJd5IqCmTJS8hFRlQlKqeK1oqZJK8kpwtkDnk29vzbsHNxRt4xRoLTsw3hUkxSEpzwgLaDyhyhrnLNRFb0No-1kQXHw3WUxNFlOTgT_bWfuyheqX_qnu73YI_I_XFyM0gHg</recordid><startdate>20150901</startdate><enddate>20150901</enddate><creator>Polyzos, N.P.</creator><creator>Sunkara, S.K.</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20150901</creationdate><title>Sub-optimal responders following controlled ovarian stimulation: an overlooked group?</title><author>Polyzos, N.P. ; Sunkara, S.K.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c365t-625a702817eb1b31839001d4ce9f09a946ef236b5be7c86a22c5fc2bc4da5d653</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adult</topic><topic>Cell Count</topic><topic>Evidence-Based Medicine</topic><topic>Female</topic><topic>Humans</topic><topic>Oocytes</topic><topic>Ovulation Induction</topic><topic>Reference Values</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Polyzos, N.P.</creatorcontrib><creatorcontrib>Sunkara, S.K.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Human reproduction (Oxford)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Polyzos, N.P.</au><au>Sunkara, S.K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sub-optimal responders following controlled ovarian stimulation: an overlooked group?</atitle><jtitle>Human reproduction (Oxford)</jtitle><addtitle>Hum Reprod</addtitle><date>2015-09-01</date><risdate>2015</risdate><volume>30</volume><issue>9</issue><spage>2005</spage><epage>2008</epage><pages>2005-2008</pages><issn>0268-1161</issn><eissn>1460-2350</eissn><abstract>Individualization of IVF treatment and tailored stimulation based on predicted ovarian response may maximize treatment success and minimize the risks following IVF. 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source | Oxford University Press Journals All Titles (1996-Current); MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
subjects | Adult Cell Count Evidence-Based Medicine Female Humans Oocytes Ovulation Induction Reference Values Treatment Outcome |
title | Sub-optimal responders following controlled ovarian stimulation: an overlooked group? |
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