Localization of the third heparin-binding site in the human complement regulator factor H

Complement factor H (fH) plays a pivotal role in regulating the alternative pathway, allowing complement activation to proceed on foreign surfaces, whilst protecting surrounding host cell surfaces from complement-mediated damage. Host cell recognition is mediated by polyanions such as sialic acid an...

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Veröffentlicht in:	Molecular Immunology 2006-04, Vol.43 (10), p.1624-1632
Hauptverfasser:	Ormsby, Rebecca J, Jokiranta, TSakari, Duthy, Thomas G, Griggs, Kim M, Sadlon, Tania A, Giannakis, Eleni, Gordon, David L
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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