Photosensitizer-Loaded pH-Responsive Hollow Gold Nanospheres for Single Light-Induced Photothermal/Photodynamic Therapy

Novel photoinduced triple-response antitumor therapeutic system based on hollow gold nanospheres (HAuNS), pH (low) insertion peptide (pHLIP), and Chlorin e6 (Ce6), was reported for the first time. The system was able to intracellularly deliver the nanocarriers by the transmembrane ability of pHLIP a...

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Veröffentlicht in:	ACS applied materials & interfaces 2015-08, Vol.7 (32), p.17592-17597
Hauptverfasser:	Yu, Meng, Guo, Fang, Wang, Jinping, Tan, Fengping, Li, Nan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Drug Carriers - chemistry Female Gold - chemistry HeLa Cells Humans Hydrogen-Ion Concentration Light Mice Mice, Nude Nanospheres - chemistry Peptides - chemistry Photochemotherapy Photosensitizing Agents - administration & dosage Photosensitizing Agents - chemistry Photosensitizing Agents - pharmacology Porphyrins - administration & dosage Porphyrins - chemistry Porphyrins - pharmacology Temperature Transplantation, Heterologous Uterine Cervical Neoplasms - drug therapy Uterine Cervical Neoplasms - pathology
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