Association of minisatellite instability with c-myc amplification and K-ras mutation in methylcholanthrene-induced mouse sarcomas

Instability of microsatellite sequences are frequently found in human tumors. In addition, minisatellite sequences, another group of highly unstable sequences, serve as sensitive markers of genetic instability. We have studied minisatellite instability in methylcholanthrene-induced mouse sarcomas. T...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1995-12, Vol.55 (23), p.5670-5676
Hauptverfasser:	NIWA, O, KAMIYA, K, FURIHATA, C, NITTA, Y, ZHONGWEN WONG, YI-JUN FAN, NINOMIYA, Y, KOTOMURA, N, NUMOTO, M, KOMINAMI, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal tumors. Experimental tumors Animals Base Sequence Biological and medical sciences DNA, Neoplasm - genetics DNA, Satellite - genetics DNA-Binding Proteins - genetics Experimental bone, joint and muscle tumors Fungal Proteins Genes, myc - genetics Genes, ras - genetics Medical sciences Methylcholanthrene Mice Micronucleus Tests Molecular Sequence Data MutS Homolog 2 Protein Point Mutation - genetics Sarcoma, Experimental - chemically induced Sarcoma, Experimental - genetics Tumors
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