Does Glp-2 have a protective effect on cerebral ischemia/reperfusion model?

To investigate the neuroprotective effects of glucagon-like peptide 2 (Glp-2), which increases cerebral blood flow, on the hippocampal complex after cerebral ischemia/reperfusion (I/R) injury in rats. Animals were randomized into 4 groups: sham, I/R + 0.9% NaCl, I/R + pre-Glp-2, and I/R + post-Glp-2...

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Veröffentlicht in:	Turkish journal of medical sciences 2015, Vol.45 (3), p.467-473
Hauptverfasser:	Topaloğlu, Naci, Memi, Gülsün, Kaner, Tuncay, Deniz, Mustafa, Şahin, Önder, Güven, Mustafa, Çoşar, Murat
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis - drug effects Brain Ischemia - metabolism Brain Ischemia - pathology Cell Death - drug effects Disease Models, Animal Glucagon-Like Peptide 2 - pharmacology Glutathione - drug effects Glutathione - metabolism Hippocampus - drug effects Hippocampus - metabolism Male Malondialdehyde - metabolism Neuroprotective Agents - pharmacology Oxidative Stress - drug effects Peroxidase - drug effects Peroxidase - metabolism Rats Rats, Sprague-Dawley Reperfusion Injury - metabolism Reperfusion Injury - prevention & control Superoxide Dismutase - drug effects Superoxide Dismutase - metabolism
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