Oncogenic rearrangements of the RET proto-oncogene in papillary thyroid carcinomas from children exposed to the Chernobyl nuclear accident

Since the Chernobyl nuclear reactor accident, a striking increase of thyroid carcinoma has been reported in children exposed to radiation in Belarus. Because of its unprecedented scale and its emotional implications, this finding has raised concern and called the attention of the scientific communit...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1995-12, Vol.55 (23), p.5617-5620
Hauptverfasser:	FUGAZZOLA, L, PILOTTI, S, PACINI, F, PIEROTTI, M. A, PINCHERA, A, VORONTSOVA, T. V, MONDELLINI, P, BONGARZONE, I, GRECO, A, ASTAKHOVA, L, BUTTI, M. G, DEMIDCHIK, E. P
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Animals Base Sequence Biological and medical sciences Blotting, Southern Carcinoma, Papillary - genetics Child Child, Preschool DNA Primers - chemistry Endocrinopathies Female Gene Expression Regulation, Neoplastic Gene Rearrangement Humans Infant Male Malignant tumors Medical sciences Mice Molecular Sequence Data Neoplasms, Radiation-Induced - genetics Proto-Oncogene Proteins - genetics Proto-Oncogenes - genetics Proto-Oncogenes - radiation effects Radioactive Fallout - adverse effects Radioactive Hazard Release Receptor Protein-Tyrosine Kinases - genetics Receptor, trkA Receptors, Nerve Growth Factor - genetics Thyroid Neoplasms - genetics Thyroid. Thyroid axis (diseases) Transfection Ukraine
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