Purification of a Mammalian Homologue of Escherichia coli Endonuclease III:  Identification of a Bovine Pyrimidine Hydrate-Thymine Glycol DNA-Glycosylase/AP Lyase by Irreversible Cross Linking to a Thymine Glycol-Containing Oligodeoxynucleotide

We purified a homologue of the Escherichia coli DNA repair enzyme endonuclease III 5000-fold from calf thymus which, like endonuclease III, demonstrates DNA-glycosylase activity against pyrimidine hydrates and thymine glycol and AP lyase activity (DNA strand cleavage at AP sites via β-elimination)....

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biochemistry (Easton) 1996-02, Vol.35 (8), p.2505-2511
Hauptverfasser:	Hilbert, Timothy P, Boorstein, Robert J, Kung, Hsiang Chuan, Bolton, Philip H, Xing, Dongxia, Cunningham, Richard P, Teebor, George W
Format:	Artikel
Sprache:	eng
Schlagworte:	Escherichia coli
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!