Association between single-nucleotide polymorphisms and milk production traits in buffalo
The aim of this study was to identify single-nucleotide polymorphisms (SNPs) in buffaloes associated with milk yield and content, in addition to somatic cell scores based on the cross-species transferability of SNPs from cattle to buffalo. A total of 15,745 SNPs were analyzed, of which 1562 showed 1...
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| Veröffentlicht in: | Genetics and molecular research 2014-12, Vol.13 (4), p.10256-10268 |
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| container_title | Genetics and molecular research |
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| creator | Venturini, G C Cardoso, D F Baldi, F Freitas, A C Aspilcueta-Borquis, R R Santos, D J A Camargo, G M F Stafuzza, N B Albuquerque, L G Tonhati, H |
| description | The aim of this study was to identify single-nucleotide polymorphisms (SNPs) in buffaloes associated with milk yield and content, in addition to somatic cell scores based on the cross-species transferability of SNPs from cattle to buffalo. A total of 15,745 SNPs were analyzed, of which 1562 showed 1% significance and 4742 with 5% significance, which were associated for all traits studied. After application of Bonferroni's correction for multiple tests of the traits analyzed, we found 2 significant SNPs placed on cattle chromosomes BTA15 and BTA20, which are homologous to buffalo chromosomes BBU16 and BBU19, respectively. In this genome association study, we found several significant SNPs affecting buffalo milk production and quality. Furthermore, the use of the high-density bovine BeadChip was suitable for genomic analysis in buffaloes. Although extensive chromosome arm homology was described between cattle and buffalo, the exact chromosomal position of SNP markers associated with these economically important traits in buffalo can be determined only through buffalo genome sequencing. |
| doi_str_mv | 10.4238/2014.December.4.20 |
| format | Article |
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Although extensive chromosome arm homology was described between cattle and buffalo, the exact chromosomal position of SNP markers associated with these economically important traits in buffalo can be determined only through buffalo genome sequencing.</description><subject>Animals</subject><subject>Buffaloes - genetics</subject><subject>Cattle</subject><subject>Chromosomes, Mammalian</subject><subject>Female</subject><subject>Genetic Markers</subject><subject>Genome-Wide Association Study - veterinary</subject><subject>Genotype</subject><subject>Lactation</subject><subject>Polymorphism, Single Nucleotide</subject><subject>Quantitative Trait Loci</subject><issn>1676-5680</issn><issn>1676-5680</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkD9PwzAQxS0EoqXwBRhQRpaEs504zliVv1IlFhiYLMc5gyGJS5wI9duT0haxMb076b2nux8h5xSSlHF5xYCmyTUabErskjRhcECmVOQizoSEwz_zhJyE8A7AslTCMZmwLAPKeD4lL_MQvHG6d76NSuy_ENsouPa1xrgdTI2-dxVGK1-vG9-t3lxoQqTbKmpc_RGtOl8N5ifbd9r1IXJjy2Ctrv0pORol4NlOZ-T59uZpcR8vH-8eFvNlbLiEPi51oUspMwo65wJTywvJCyE5pVZAhSCt5SwzVto0h_FlgNwAmDKzGgo0fEYut73jMZ8Dhl41Lhisa92iH4KiOWSQU0Hl_1bB86JIOROjlW2tpvMhdGjVqnON7taKgtrQVxv6ak9fpeM-hi52_UPZYPUb2ePm38WWgu8</recordid><startdate>20141204</startdate><enddate>20141204</enddate><creator>Venturini, G C</creator><creator>Cardoso, D F</creator><creator>Baldi, F</creator><creator>Freitas, A C</creator><creator>Aspilcueta-Borquis, R R</creator><creator>Santos, D J A</creator><creator>Camargo, G M F</creator><creator>Stafuzza, N B</creator><creator>Albuquerque, L G</creator><creator>Tonhati, H</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7TM</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope></search><sort><creationdate>20141204</creationdate><title>Association between single-nucleotide polymorphisms and milk production traits in buffalo</title><author>Venturini, G C ; 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| subjects | Animals Buffaloes - genetics Cattle Chromosomes, Mammalian Female Genetic Markers Genome-Wide Association Study - veterinary Genotype Lactation Polymorphism, Single Nucleotide Quantitative Trait Loci |
| title | Association between single-nucleotide polymorphisms and milk production traits in buffalo |
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