Development and Characterization of a Scaffold-Free 3D Spheroid Model of Induced Pluripotent Stem Cell-Derived Human Cardiomyocytes

Cardiomyocytes (CMs) are terminally differentiated cells in the adult heart, and ischemia and cardiotoxic compounds can lead to cell death and irreversible decline of cardiac function. As testing platforms, isolated organs and primary cells from rodents have been the standard in research and toxicol...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Tissue engineering. Part C, Methods Methods, 2015-08, Vol.21 (8), p.852-861
Hauptverfasser:	Beauchamp, Philippe, Moritz, Wolfgang, Kelm, Jens M., Ullrich, Nina D., Agarkova, Irina, Anson, Blake D., Suter, Thomas M., Zuppinger, Christian
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Calcium Signaling Connexin 43 - metabolism Humans Induced Pluripotent Stem Cells - cytology Induced Pluripotent Stem Cells - metabolism Matrix Models, Cardiovascular Myocytes, Cardiac - cytology Myocytes, Cardiac - metabolism Proteins Spheroids, Cellular - cytology Spheroids, Cellular - metabolism Stem cells Studies Tissue Scaffolds - chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!