Platelet-Rich Plasma Injections for the Treatment of Hamstring Injuries: A Randomized Controlled Trial
Background: A hamstring injury is one of the most common types of injury affecting athletes. Despite this, the optimal management of hamstring muscle injuries is not yet defined. The effect of autologous platelet-rich plasma (PRP) therapy on the recovery of hamstring injuries is unclear. Purpose: To...
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| Veröffentlicht in: | The American journal of sports medicine 2014-10, Vol.42 (10), p.2410-2418 |
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| container_title | The American journal of sports medicine |
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| creator | A Hamid, Mohamad Shariff Mohamed Ali, Mohamed Razif Yusof, Ashril George, John Lee, Leena Poh Chen |
| description | Background:
A hamstring injury is one of the most common types of injury affecting athletes. Despite this, the optimal management of hamstring muscle injuries is not yet defined. The effect of autologous platelet-rich plasma (PRP) therapy on the recovery of hamstring injuries is unclear.
Purpose:
To investigate the effect of a single PRP injection in the treatment of grade 2 hamstring muscle injuries.
Study Design:
Randomized controlled trial; Level of evidence, 2.
Methods:
Twenty-eight patients diagnosed with an acute hamstring injury were randomly allocated to autologous PRP therapy combined with a rehabilitation program or a rehabilitation program only. The primary outcome of this study was time to return to play. In addition, changes in pain severity and pain interference scores over time were examined.
Results:
Patients in the PRP group achieved full recovery significantly earlier than controls (P = .02). The mean time to return to play was 42.5 ± 20.6 days in the control group and 26.7 ± 7.0 days in the PRP group. Significantly lower pain severity scores were observed in the PRP group throughout the study. However, no significant difference in the pain interference score was found between the 2 groups.
Conclusion:
A single autologous PRP injection combined with a rehabilitation program was significantly more effective in treating hamstring injuries than a rehabilitation program alone. |
| doi_str_mv | 10.1177/0363546514541540 |
| format | Article |
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A hamstring injury is one of the most common types of injury affecting athletes. Despite this, the optimal management of hamstring muscle injuries is not yet defined. The effect of autologous platelet-rich plasma (PRP) therapy on the recovery of hamstring injuries is unclear.
Purpose:
To investigate the effect of a single PRP injection in the treatment of grade 2 hamstring muscle injuries.
Study Design:
Randomized controlled trial; Level of evidence, 2.
Methods:
Twenty-eight patients diagnosed with an acute hamstring injury were randomly allocated to autologous PRP therapy combined with a rehabilitation program or a rehabilitation program only. The primary outcome of this study was time to return to play. In addition, changes in pain severity and pain interference scores over time were examined.
Results:
Patients in the PRP group achieved full recovery significantly earlier than controls (P = .02). The mean time to return to play was 42.5 ± 20.6 days in the control group and 26.7 ± 7.0 days in the PRP group. Significantly lower pain severity scores were observed in the PRP group throughout the study. However, no significant difference in the pain interference score was found between the 2 groups.
Conclusion:
A single autologous PRP injection combined with a rehabilitation program was significantly more effective in treating hamstring injuries than a rehabilitation program alone.</description><identifier>ISSN: 0363-5465</identifier><identifier>EISSN: 1552-3365</identifier><identifier>DOI: 10.1177/0363546514541540</identifier><identifier>PMID: 25073598</identifier><identifier>CODEN: AJSMDO</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Adolescent ; Adult ; Athletic Injuries - therapy ; Blood platelets ; Clinical trials ; Exercise Therapy ; Female ; Humans ; Injections ; Injections, Intramuscular ; Injuries ; Knee ; Lower Extremity - injuries ; Male ; Middle Aged ; Muscle, Skeletal - injuries ; Muscular system ; Pain ; Pain Measurement ; Plasma ; Platelet Transfusion - methods ; Platelet-Rich Plasma ; Recovery of Function ; Regression Analysis ; Rehabilitation ; Single-Blind Method ; Sports injuries ; Sports medicine ; Time Factors</subject><ispartof>The American journal of sports medicine, 2014-10, Vol.42 (10), p.2410-2418</ispartof><rights>2014 The Author(s)</rights><rights>2014 The Author(s).</rights><rights>Copyright Sage Publications Ltd. Oct 2014</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c379t-179daca823fe043f00e8bfd75e72c3d52b52563e817415c1302647f6e5d66af33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/0363546514541540$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/0363546514541540$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,776,780,21799,27903,27904,43600,43601</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25073598$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>A Hamid, Mohamad Shariff</creatorcontrib><creatorcontrib>Mohamed Ali, Mohamed Razif</creatorcontrib><creatorcontrib>Yusof, Ashril</creatorcontrib><creatorcontrib>George, John</creatorcontrib><creatorcontrib>Lee, Leena Poh Chen</creatorcontrib><title>Platelet-Rich Plasma Injections for the Treatment of Hamstring Injuries: A Randomized Controlled Trial</title><title>The American journal of sports medicine</title><addtitle>Am J Sports Med</addtitle><description>Background:
A hamstring injury is one of the most common types of injury affecting athletes. Despite this, the optimal management of hamstring muscle injuries is not yet defined. The effect of autologous platelet-rich plasma (PRP) therapy on the recovery of hamstring injuries is unclear.
Purpose:
To investigate the effect of a single PRP injection in the treatment of grade 2 hamstring muscle injuries.
Study Design:
Randomized controlled trial; Level of evidence, 2.
Methods:
Twenty-eight patients diagnosed with an acute hamstring injury were randomly allocated to autologous PRP therapy combined with a rehabilitation program or a rehabilitation program only. The primary outcome of this study was time to return to play. In addition, changes in pain severity and pain interference scores over time were examined.
Results:
Patients in the PRP group achieved full recovery significantly earlier than controls (P = .02). The mean time to return to play was 42.5 ± 20.6 days in the control group and 26.7 ± 7.0 days in the PRP group. Significantly lower pain severity scores were observed in the PRP group throughout the study. However, no significant difference in the pain interference score was found between the 2 groups.
Conclusion:
A single autologous PRP injection combined with a rehabilitation program was significantly more effective in treating hamstring injuries than a rehabilitation program alone.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Athletic Injuries - therapy</subject><subject>Blood platelets</subject><subject>Clinical trials</subject><subject>Exercise Therapy</subject><subject>Female</subject><subject>Humans</subject><subject>Injections</subject><subject>Injections, Intramuscular</subject><subject>Injuries</subject><subject>Knee</subject><subject>Lower Extremity - injuries</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Muscle, Skeletal - injuries</subject><subject>Muscular system</subject><subject>Pain</subject><subject>Pain Measurement</subject><subject>Plasma</subject><subject>Platelet Transfusion - methods</subject><subject>Platelet-Rich Plasma</subject><subject>Recovery of Function</subject><subject>Regression Analysis</subject><subject>Rehabilitation</subject><subject>Single-Blind Method</subject><subject>Sports injuries</subject><subject>Sports medicine</subject><subject>Time Factors</subject><issn>0363-5465</issn><issn>1552-3365</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkctLxDAQxoMouj7unqTgxUt1knSS5iii7oKgiJ5Ltp1olz40SQ_-97asigjqaRjmN988PsYOOZxyrvUZSCUxU8gzzDhmsMFmHFGkUircZLOpnE71HbYbwgoAuFb5NtsRCFqiyWfs-q6xkRqK6X1dPidjFlqbLLoVlbHuu5C43ifxmZIHTza21MWkd8nctiH6unuayMHXFPbZlrNNoIOPuMcery4fLubpze314uL8Ji2lNjHl2lS2tLmQjiCTDoDypas0khalrFAsUaCSlHM9HlRyCUJl2inCSinrpNxjJ2vdF9-_DhRi0dahpKaxHfVDKLgGBCUywP9RzBUYI_JsRI9_oKt-8N14SMGNlNKgGR_2F6XGVcEIPW0Ia6r0fQieXPHi69b6t4JDMblW_HRtbDn6EB6WLVVfDZ82jUC6BoJ9om9TfxN8B8BQmxM</recordid><startdate>20141001</startdate><enddate>20141001</enddate><creator>A Hamid, Mohamad Shariff</creator><creator>Mohamed Ali, Mohamed Razif</creator><creator>Yusof, Ashril</creator><creator>George, John</creator><creator>Lee, Leena Poh Chen</creator><general>SAGE Publications</general><general>Sage Publications Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TS</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>U9A</scope><scope>7X8</scope></search><sort><creationdate>20141001</creationdate><title>Platelet-Rich Plasma Injections for the Treatment of Hamstring Injuries</title><author>A Hamid, Mohamad Shariff ; Mohamed Ali, Mohamed Razif ; Yusof, Ashril ; George, John ; Lee, Leena Poh Chen</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c379t-179daca823fe043f00e8bfd75e72c3d52b52563e817415c1302647f6e5d66af33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Athletic Injuries - therapy</topic><topic>Blood platelets</topic><topic>Clinical trials</topic><topic>Exercise Therapy</topic><topic>Female</topic><topic>Humans</topic><topic>Injections</topic><topic>Injections, Intramuscular</topic><topic>Injuries</topic><topic>Knee</topic><topic>Lower Extremity - injuries</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Muscle, Skeletal - injuries</topic><topic>Muscular system</topic><topic>Pain</topic><topic>Pain Measurement</topic><topic>Plasma</topic><topic>Platelet Transfusion - methods</topic><topic>Platelet-Rich Plasma</topic><topic>Recovery of Function</topic><topic>Regression Analysis</topic><topic>Rehabilitation</topic><topic>Single-Blind Method</topic><topic>Sports injuries</topic><topic>Sports medicine</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>A Hamid, Mohamad Shariff</creatorcontrib><creatorcontrib>Mohamed Ali, Mohamed Razif</creatorcontrib><creatorcontrib>Yusof, Ashril</creatorcontrib><creatorcontrib>George, John</creatorcontrib><creatorcontrib>Lee, Leena Poh Chen</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Physical Education Index</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of sports medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>A Hamid, Mohamad Shariff</au><au>Mohamed Ali, Mohamed Razif</au><au>Yusof, Ashril</au><au>George, John</au><au>Lee, Leena Poh Chen</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Platelet-Rich Plasma Injections for the Treatment of Hamstring Injuries: A Randomized Controlled Trial</atitle><jtitle>The American journal of sports medicine</jtitle><addtitle>Am J Sports Med</addtitle><date>2014-10-01</date><risdate>2014</risdate><volume>42</volume><issue>10</issue><spage>2410</spage><epage>2418</epage><pages>2410-2418</pages><issn>0363-5465</issn><eissn>1552-3365</eissn><coden>AJSMDO</coden><abstract>Background:
A hamstring injury is one of the most common types of injury affecting athletes. Despite this, the optimal management of hamstring muscle injuries is not yet defined. The effect of autologous platelet-rich plasma (PRP) therapy on the recovery of hamstring injuries is unclear.
Purpose:
To investigate the effect of a single PRP injection in the treatment of grade 2 hamstring muscle injuries.
Study Design:
Randomized controlled trial; Level of evidence, 2.
Methods:
Twenty-eight patients diagnosed with an acute hamstring injury were randomly allocated to autologous PRP therapy combined with a rehabilitation program or a rehabilitation program only. The primary outcome of this study was time to return to play. In addition, changes in pain severity and pain interference scores over time were examined.
Results:
Patients in the PRP group achieved full recovery significantly earlier than controls (P = .02). The mean time to return to play was 42.5 ± 20.6 days in the control group and 26.7 ± 7.0 days in the PRP group. Significantly lower pain severity scores were observed in the PRP group throughout the study. However, no significant difference in the pain interference score was found between the 2 groups.
Conclusion:
A single autologous PRP injection combined with a rehabilitation program was significantly more effective in treating hamstring injuries than a rehabilitation program alone.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>25073598</pmid><doi>10.1177/0363546514541540</doi><tpages>9</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0363-5465 |
| ispartof | The American journal of sports medicine, 2014-10, Vol.42 (10), p.2410-2418 |
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| source | MEDLINE; SAGE Complete; Alma/SFX Local Collection |
| subjects | Adolescent Adult Athletic Injuries - therapy Blood platelets Clinical trials Exercise Therapy Female Humans Injections Injections, Intramuscular Injuries Knee Lower Extremity - injuries Male Middle Aged Muscle, Skeletal - injuries Muscular system Pain Pain Measurement Plasma Platelet Transfusion - methods Platelet-Rich Plasma Recovery of Function Regression Analysis Rehabilitation Single-Blind Method Sports injuries Sports medicine Time Factors |
| title | Platelet-Rich Plasma Injections for the Treatment of Hamstring Injuries: A Randomized Controlled Trial |
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