NMDA and non-NMDA receptors stimulation causes differential oxidative stress in rat cortical slices

Glutamate receptor activated neuronal cell death is attributed to a massive influx of Ca 2+ and subsequent formation of reactive oxygen species (ROS) but the relative contribution of NMDA and non-NMDA sub-types of glutamate receptors in excitotoxicity is not known. In the present study, we have exam...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neurochemistry international 2006-10, Vol.49 (5), p.475-480
Hauptverfasser:	Sanganahalli, Basavaraju G., Joshi, Preeti G., Joshi, Nanda B.
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid - pharmacology Animals Biological and medical sciences Cerebral Cortex - drug effects Cerebral Cortex - enzymology Cerebral Cortex - metabolism Cortical slices Excitotoxicity Fundamental and applied biological sciences. Psychology Kainic Acid - pharmacology L-Lactate Dehydrogenase - metabolism Mitochondrial depolarization N-Methylaspartate - pharmacology Oxidative Stress Rats Rats, Sprague-Dawley Reactive Oxygen Species Receptors, N-Methyl-D-Aspartate - agonists Spectrometry, Fluorescence Vertebrates: nervous system and sense organs
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!