$Campath-1H, a humanized monoclonal antibody, in refractory rheumatoid arthritis : an intravenous dose-escalation study$

Campath-1H, a humanized monoclonal antibody, in refractory rheumatoid arthritis : an intravenous dose-escalation study

To evaluate the biologic response, tolerability, and potential clinical effect of a humanized antilymphocyte monoclonal antibody, CAMPATH-1H, in patients with rheumatoid arthritis (RA). Forty adult patients with active, refractory RA were treated with CAMPATH-1H, given intravenously, in a multicente...

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Veröffentlicht in:	Arthritis and rheumatism 1995-11, Vol.38 (11), p.1589-1594
Hauptverfasser:	WEINBLATT, M. E, MADDISON, P. J, JOHNSTON, J. M, BULPITT, K. J, HAZLEMAN, B. L, UROWITZ, M. B, STURROCK, R. D, COBLYN, J. S, MAIER, A. L, SPREEN, W. R, MANNA, V. K
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alemtuzumab Antibodies, Monoclonal - administration & dosage Antibodies, Monoclonal - adverse effects Antibodies, Monoclonal - immunology Antibodies, Monoclonal - therapeutic use Antibodies, Monoclonal, Humanized Antibodies, Neoplasm Arthritis, Rheumatoid - therapy Biological and medical sciences Bones, joints and connective tissue. Antiinflammatory agents Cohort Studies Dose-Response Relationship, Immunologic Drug Tolerance Humans Injections, Intravenous Medical sciences Pharmacology. Drug treatments
Online-Zugang:	Volltext
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