A Prospective Randomized Trial Comparing Pneumatic Lithotripsy and Holmium Laser for Management of Middle and Distal Ureteral Calculi

The aim of this study was to compare the efficacy and safety between pneumatic and holmium:yttrium-aluminum-garnet (Ho:YAG) laser in the treatment of patients with ureteral stones located in the middle and distal ureter. We conducted a prospective study in recruiting 982 eligible patients from 2009...

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Veröffentlicht in:Journal of endourology 2015-08, Vol.29 (8), p.883-887
Hauptverfasser: Li, Linjin, Pan, Yue, Weng, Zhiliang, Bao, Wenshuo, Yu, Zhixian, Wang, Feng
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container_end_page 887
container_issue 8
container_start_page 883
container_title Journal of endourology
container_volume 29
creator Li, Linjin
Pan, Yue
Weng, Zhiliang
Bao, Wenshuo
Yu, Zhixian
Wang, Feng
description The aim of this study was to compare the efficacy and safety between pneumatic and holmium:yttrium-aluminum-garnet (Ho:YAG) laser in the treatment of patients with ureteral stones located in the middle and distal ureter. We conducted a prospective study in recruiting 982 eligible patients from 2009 to 2012. Patients were randomly divided into two groups-the pneumatic lithotripsy (PL) group or the Ho:YAG laser lithotripsy (LL) group. Patient demographics, stone characteristics, intraoperative parameters, and postoperative complications were evaluated and analyzed. The baseline demographics of patients and stone characteristics were similar in the two groups. The LL group showed significant benefits compared with the PL group in terms of mean operative time (28±9.2 vs 41±12.4 min, P=0.001) and early stone-free rate (80.8% vs 91.3%, P=0.04), but there was no statistically significant difference at the third month (92.6% vs 95.5%, P=0.15). In the LL group, 24 postoperative cases of stricture were seen, whereas only 5 cases occurred in the PL group (P=0.02). The other complications, such as perforation, bleeding, and mucosal injury, were comparable in the two groups. The average postoperative stay was also similar (1.7±2.4 days for PL and 1.5±3.1 days for LL (P=0.62). Both PL and LL are effective in the management of middle and distal impacted stones. Ho:YAG laser has advantages in better efficacy of stone fragmentation and a higher early stone-free rate but seems to have to face the increased risks of postoperative stricture.
doi_str_mv 10.1089/end.2014.0856
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source MEDLINE; Alma/SFX Local Collection
subjects Adult
Aged
Constriction, Pathologic - surgery
Female
Holmium - therapeutic use
Humans
Lasers, Solid-State - therapeutic use
Lithotripsy, Laser - adverse effects
Lithotripsy, Laser - methods
Male
Middle Aged
Operative Time
Postoperative Complications - etiology
Postoperative Period
Prospective Studies
Ureteral Calculi - surgery
title A Prospective Randomized Trial Comparing Pneumatic Lithotripsy and Holmium Laser for Management of Middle and Distal Ureteral Calculi
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