Factors Associated With and Outcomes After Ventricular Fibrillation Before and During Primary Angioplasty in Patients With ST-Segment Elevation Myocardial Infarction
We aimed to assess the risk factors and outcome of ventricular fibrillation (VF) before and during primary percutaneous coronary intervention (PPCI) in patients with ST-segment elevation myocardial infarction. From 1999 to 2012, we consecutively enrolled 5,373 patients with ST-segment elevation myoc...
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Veröffentlicht in: | The American journal of cardiology 2015-09, Vol.116 (5), p.678-685 |
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creator | Jabbari, Reza, MD, PhD Risgaard, Bjarke, MD, PhD Fosbøl, Emil L., MD, PhD Scheike, Thomas, PhD Philbert, Berit T., MD, PhD Winkel, Bo G., MD, PhD Albert, Christine M., MD, MPH Glinge, Charlotte, MD Ahtarovski, Kiril A., MD, PhD Haunsø, Stig, MD, DMSci Køber, Lars, MD, DMSci Jørgensen, Erik, MD Pedersen, Frants, MD, PhD Tfelt-Hansen, Jacob, MD, DMSci Engstrøm, Thomas, MD, PhD, DMSci |
description | We aimed to assess the risk factors and outcome of ventricular fibrillation (VF) before and during primary percutaneous coronary intervention (PPCI) in patients with ST-segment elevation myocardial infarction. From 1999 to 2012, we consecutively enrolled 5,373 patients with ST-segment elevation myocardial infarction. In total, 410 of the patients had VF before and 88 had VF during PPCI. During a mean follow-up of 4.2 years, 1,196 subjects died. A logistic regression model identified younger age, anterior infarct, Killip class >I at admission, and a preprocedural Thrombolysis In Myocardial Infarction flow grade of 0 to I to be significantly associated with VF before PPCI, whereas inferior infarct, a preprocedural Thrombolysis In Myocardial Infarction flow grade of 0 to I, and Killip class >I at admission were significantly associated with VF during PPCI. All-cause mortality was evaluated using the Cox regression model. Compared with the patients without VF, those with VF before or during PPCI had a significantly increased 30-day mortality, with an adjusted hazard ratio = 3.40 (95% confidence interval 1.70 to 6.70) and 4.20 (95% confidence interval 1.30 to 13.30), respectively. Importantly, there was no tendency of 30-day mortality difference between VF before and during PPCI (p = 0.170). In patients with VF before or during PPCI who survived for at least 30 days, there was no increase in the long-term mortality. In conclusion, our data suggest that 30-day mortality is the same for patients with VF before PPCI compared with VF during PPCI, and the occurrence of VF before or during PPCI was associated with increased 30-day mortality but not with long-term mortality. |
doi_str_mv | 10.1016/j.amjcard.2015.05.037 |
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From 1999 to 2012, we consecutively enrolled 5,373 patients with ST-segment elevation myocardial infarction. In total, 410 of the patients had VF before and 88 had VF during PPCI. During a mean follow-up of 4.2 years, 1,196 subjects died. A logistic regression model identified younger age, anterior infarct, Killip class >I at admission, and a preprocedural Thrombolysis In Myocardial Infarction flow grade of 0 to I to be significantly associated with VF before PPCI, whereas inferior infarct, a preprocedural Thrombolysis In Myocardial Infarction flow grade of 0 to I, and Killip class >I at admission were significantly associated with VF during PPCI. All-cause mortality was evaluated using the Cox regression model. Compared with the patients without VF, those with VF before or during PPCI had a significantly increased 30-day mortality, with an adjusted hazard ratio = 3.40 (95% confidence interval 1.70 to 6.70) and 4.20 (95% confidence interval 1.30 to 13.30), respectively. Importantly, there was no tendency of 30-day mortality difference between VF before and during PPCI (p = 0.170). In patients with VF before or during PPCI who survived for at least 30 days, there was no increase in the long-term mortality. In conclusion, our data suggest that 30-day mortality is the same for patients with VF before PPCI compared with VF during PPCI, and the occurrence of VF before or during PPCI was associated with increased 30-day mortality but not with long-term mortality.</description><identifier>ISSN: 0002-9149</identifier><identifier>EISSN: 1879-1913</identifier><identifier>DOI: 10.1016/j.amjcard.2015.05.037</identifier><identifier>PMID: 26150175</identifier><identifier>CODEN: AJCDAG</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Aged ; Angina pectoris ; Angioplasty ; Angioplasty, Balloon, Coronary ; Cardiovascular ; Cause of Death - trends ; Denmark - epidemiology ; Electrocardiography ; Female ; Follow-Up Studies ; Heart attacks ; Humans ; Intraoperative Period ; Male ; Middle Aged ; Mortality ; Myocardial Infarction - complications ; Myocardial Infarction - diagnosis ; Myocardial Infarction - surgery ; Preoperative Period ; Prognosis ; Retrospective Studies ; Survival Rate - trends ; Time Factors ; Treatment Outcome ; Ventricular Fibrillation - etiology ; Ventricular Fibrillation - mortality ; Ventricular Fibrillation - physiopathology</subject><ispartof>The American journal of cardiology, 2015-09, Vol.116 (5), p.678-685</ispartof><rights>Elsevier Inc.</rights><rights>2015 Elsevier Inc.</rights><rights>Copyright © 2015 Elsevier Inc. All rights reserved.</rights><rights>Copyright Elsevier Limited Sep 1, 2015</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c518t-587baa82d083320b95b97d019b609e81de3978e421509efe3495c593c617ac803</citedby><cites>FETCH-LOGICAL-c518t-587baa82d083320b95b97d019b609e81de3978e421509efe3495c593c617ac803</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/1708147849?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,3549,27923,27924,45994,64384,64386,64388,72240</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26150175$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jabbari, Reza, MD, PhD</creatorcontrib><creatorcontrib>Risgaard, Bjarke, MD, PhD</creatorcontrib><creatorcontrib>Fosbøl, Emil L., MD, PhD</creatorcontrib><creatorcontrib>Scheike, Thomas, PhD</creatorcontrib><creatorcontrib>Philbert, Berit T., MD, PhD</creatorcontrib><creatorcontrib>Winkel, Bo G., MD, PhD</creatorcontrib><creatorcontrib>Albert, Christine M., MD, MPH</creatorcontrib><creatorcontrib>Glinge, Charlotte, MD</creatorcontrib><creatorcontrib>Ahtarovski, Kiril A., MD, PhD</creatorcontrib><creatorcontrib>Haunsø, Stig, MD, DMSci</creatorcontrib><creatorcontrib>Køber, Lars, MD, DMSci</creatorcontrib><creatorcontrib>Jørgensen, Erik, MD</creatorcontrib><creatorcontrib>Pedersen, Frants, MD, PhD</creatorcontrib><creatorcontrib>Tfelt-Hansen, Jacob, MD, DMSci</creatorcontrib><creatorcontrib>Engstrøm, Thomas, MD, PhD, DMSci</creatorcontrib><title>Factors Associated With and Outcomes After Ventricular Fibrillation Before and During Primary Angioplasty in Patients With ST-Segment Elevation Myocardial Infarction</title><title>The American journal of cardiology</title><addtitle>Am J Cardiol</addtitle><description>We aimed to assess the risk factors and outcome of ventricular fibrillation (VF) before and during primary percutaneous coronary intervention (PPCI) in patients with ST-segment elevation myocardial infarction. From 1999 to 2012, we consecutively enrolled 5,373 patients with ST-segment elevation myocardial infarction. In total, 410 of the patients had VF before and 88 had VF during PPCI. During a mean follow-up of 4.2 years, 1,196 subjects died. A logistic regression model identified younger age, anterior infarct, Killip class >I at admission, and a preprocedural Thrombolysis In Myocardial Infarction flow grade of 0 to I to be significantly associated with VF before PPCI, whereas inferior infarct, a preprocedural Thrombolysis In Myocardial Infarction flow grade of 0 to I, and Killip class >I at admission were significantly associated with VF during PPCI. All-cause mortality was evaluated using the Cox regression model. Compared with the patients without VF, those with VF before or during PPCI had a significantly increased 30-day mortality, with an adjusted hazard ratio = 3.40 (95% confidence interval 1.70 to 6.70) and 4.20 (95% confidence interval 1.30 to 13.30), respectively. Importantly, there was no tendency of 30-day mortality difference between VF before and during PPCI (p = 0.170). In patients with VF before or during PPCI who survived for at least 30 days, there was no increase in the long-term mortality. In conclusion, our data suggest that 30-day mortality is the same for patients with VF before PPCI compared with VF during PPCI, and the occurrence of VF before or during PPCI was associated with increased 30-day mortality but not with long-term mortality.</description><subject>Aged</subject><subject>Angina pectoris</subject><subject>Angioplasty</subject><subject>Angioplasty, Balloon, Coronary</subject><subject>Cardiovascular</subject><subject>Cause of Death - trends</subject><subject>Denmark - epidemiology</subject><subject>Electrocardiography</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Heart attacks</subject><subject>Humans</subject><subject>Intraoperative Period</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Myocardial Infarction - complications</subject><subject>Myocardial Infarction - diagnosis</subject><subject>Myocardial Infarction - surgery</subject><subject>Preoperative Period</subject><subject>Prognosis</subject><subject>Retrospective Studies</subject><subject>Survival Rate - 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trends</topic><topic>Denmark - epidemiology</topic><topic>Electrocardiography</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Heart attacks</topic><topic>Humans</topic><topic>Intraoperative Period</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Myocardial Infarction - complications</topic><topic>Myocardial Infarction - diagnosis</topic><topic>Myocardial Infarction - surgery</topic><topic>Preoperative Period</topic><topic>Prognosis</topic><topic>Retrospective Studies</topic><topic>Survival Rate - trends</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><topic>Ventricular Fibrillation - etiology</topic><topic>Ventricular Fibrillation - mortality</topic><topic>Ventricular Fibrillation - physiopathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jabbari, Reza, MD, PhD</creatorcontrib><creatorcontrib>Risgaard, Bjarke, MD, PhD</creatorcontrib><creatorcontrib>Fosbøl, Emil L., MD, PhD</creatorcontrib><creatorcontrib>Scheike, Thomas, PhD</creatorcontrib><creatorcontrib>Philbert, Berit T., MD, PhD</creatorcontrib><creatorcontrib>Winkel, Bo G., MD, PhD</creatorcontrib><creatorcontrib>Albert, Christine M., MD, MPH</creatorcontrib><creatorcontrib>Glinge, Charlotte, MD</creatorcontrib><creatorcontrib>Ahtarovski, Kiril A., MD, PhD</creatorcontrib><creatorcontrib>Haunsø, Stig, MD, DMSci</creatorcontrib><creatorcontrib>Køber, Lars, MD, DMSci</creatorcontrib><creatorcontrib>Jørgensen, Erik, MD</creatorcontrib><creatorcontrib>Pedersen, Frants, MD, PhD</creatorcontrib><creatorcontrib>Tfelt-Hansen, Jacob, MD, DMSci</creatorcontrib><creatorcontrib>Engstrøm, Thomas, MD, PhD, DMSci</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Physical Education Index</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Biochemistry Abstracts 1</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jabbari, Reza, MD, PhD</au><au>Risgaard, Bjarke, MD, PhD</au><au>Fosbøl, Emil L., MD, PhD</au><au>Scheike, Thomas, PhD</au><au>Philbert, Berit T., MD, PhD</au><au>Winkel, Bo G., MD, PhD</au><au>Albert, Christine M., MD, MPH</au><au>Glinge, Charlotte, MD</au><au>Ahtarovski, Kiril A., MD, PhD</au><au>Haunsø, Stig, MD, DMSci</au><au>Køber, Lars, MD, DMSci</au><au>Jørgensen, Erik, MD</au><au>Pedersen, Frants, MD, PhD</au><au>Tfelt-Hansen, Jacob, MD, DMSci</au><au>Engstrøm, Thomas, MD, PhD, DMSci</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Factors Associated With and Outcomes After Ventricular Fibrillation Before and During Primary Angioplasty in Patients With ST-Segment Elevation Myocardial Infarction</atitle><jtitle>The American journal of cardiology</jtitle><addtitle>Am J Cardiol</addtitle><date>2015-09-01</date><risdate>2015</risdate><volume>116</volume><issue>5</issue><spage>678</spage><epage>685</epage><pages>678-685</pages><issn>0002-9149</issn><eissn>1879-1913</eissn><coden>AJCDAG</coden><abstract>We aimed to assess the risk factors and outcome of ventricular fibrillation (VF) before and during primary percutaneous coronary intervention (PPCI) in patients with ST-segment elevation myocardial infarction. From 1999 to 2012, we consecutively enrolled 5,373 patients with ST-segment elevation myocardial infarction. In total, 410 of the patients had VF before and 88 had VF during PPCI. During a mean follow-up of 4.2 years, 1,196 subjects died. A logistic regression model identified younger age, anterior infarct, Killip class >I at admission, and a preprocedural Thrombolysis In Myocardial Infarction flow grade of 0 to I to be significantly associated with VF before PPCI, whereas inferior infarct, a preprocedural Thrombolysis In Myocardial Infarction flow grade of 0 to I, and Killip class >I at admission were significantly associated with VF during PPCI. All-cause mortality was evaluated using the Cox regression model. Compared with the patients without VF, those with VF before or during PPCI had a significantly increased 30-day mortality, with an adjusted hazard ratio = 3.40 (95% confidence interval 1.70 to 6.70) and 4.20 (95% confidence interval 1.30 to 13.30), respectively. Importantly, there was no tendency of 30-day mortality difference between VF before and during PPCI (p = 0.170). In patients with VF before or during PPCI who survived for at least 30 days, there was no increase in the long-term mortality. In conclusion, our data suggest that 30-day mortality is the same for patients with VF before PPCI compared with VF during PPCI, and the occurrence of VF before or during PPCI was associated with increased 30-day mortality but not with long-term mortality.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>26150175</pmid><doi>10.1016/j.amjcard.2015.05.037</doi><tpages>8</tpages></addata></record> |
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subjects | Aged Angina pectoris Angioplasty Angioplasty, Balloon, Coronary Cardiovascular Cause of Death - trends Denmark - epidemiology Electrocardiography Female Follow-Up Studies Heart attacks Humans Intraoperative Period Male Middle Aged Mortality Myocardial Infarction - complications Myocardial Infarction - diagnosis Myocardial Infarction - surgery Preoperative Period Prognosis Retrospective Studies Survival Rate - trends Time Factors Treatment Outcome Ventricular Fibrillation - etiology Ventricular Fibrillation - mortality Ventricular Fibrillation - physiopathology |
title | Factors Associated With and Outcomes After Ventricular Fibrillation Before and During Primary Angioplasty in Patients With ST-Segment Elevation Myocardial Infarction |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-09T10%3A01%3A17IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Factors%20Associated%20With%20and%20Outcomes%20After%20Ventricular%20Fibrillation%20Before%20and%20During%20Primary%20Angioplasty%20in%20Patients%20With%20ST-Segment%20Elevation%20Myocardial%20Infarction&rft.jtitle=The%20American%20journal%20of%20cardiology&rft.au=Jabbari,%20Reza,%20MD,%20PhD&rft.date=2015-09-01&rft.volume=116&rft.issue=5&rft.spage=678&rft.epage=685&rft.pages=678-685&rft.issn=0002-9149&rft.eissn=1879-1913&rft.coden=AJCDAG&rft_id=info:doi/10.1016/j.amjcard.2015.05.037&rft_dat=%3Cproquest_cross%3E3792692131%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1708147849&rft_id=info:pmid/26150175&rft_els_id=S0002914915014216&rfr_iscdi=true |