A novel CCAAT-binding protein necessary for adhesion-dependent cyclin A transcription at the G sub(1)/S boundary is sequestered by a retinoblastoma-like protein in G sub(0)
Loss of adhesion leads to cell cycle arrest at the G sub(1)/S boundary in normal, adhesion-dependent, mesenchymal cells. This arrest is accompanied by the inability to produce cyclin A. Using deletional and mutational analysis of the cyclin A promoter, we have identified a CCAAT element that mediate...
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| Veröffentlicht in: | The Journal of biological chemistry 1996-01, Vol.271 (12), p.6579-6582 |
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| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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