Subchronic toxicity studies with the leuko-triene D sub(4) antagonist RG 12525

Preclinical safety studies with the leukotriene D sub(4) antagonist RG 12525 were conducted by the oral route in mice, rats, and monkeys. Oral administration of RG 12525 was repeated daily in studies up to 6 months in duration. RG 12525 was shown to have limited high-dose toxicity after repeated ora...

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Veröffentlicht in:Fundamental and applied toxicology 1995-01, Vol.28 (1), p.129-138
Hauptverfasser: Bonnefoi, MS, Kelley, M F, Wells, R E, Sanders, JE, Jayyosi, Z, Beys, E, Kornbrust, D J, Langloss, J M
Format: Artikel
Sprache:eng
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