Tenuigenin ameliorates acute lung injury by inhibiting NF-κB and MAPK signalling pathways

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Veröffentlicht in:	Respiratory physiology & neurobiology 2015-09, Vol.216, p.43-51
Hauptverfasser:	Lv, Hongming, Zhu, Chao, Liao, Yuanjun, Gao, Yawen, Lu, Gejin, Zhong, Weiting, Zheng, Yuwei, Chen, Wei, Ci, Xinxin
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute lung injury Acute Lung Injury - chemically induced Acute Lung Injury - drug therapy Acute Lung Injury - pathology Animals Anti-Inflammatory Agents - pharmacology Anti-Inflammatory Agents - therapeutic use Bronchoalveolar Lavage Fluid - chemistry Cell Line, Transformed Cell Survival - drug effects Cyclooxygenase 2 - metabolism Cytokines - metabolism Dexamethasone - pharmacology Dexamethasone - therapeutic use Disease Models, Animal Dose-Response Relationship, Drug Drugs, Chinese Herbal - chemistry Drugs, Chinese Herbal - pharmacology Drugs, Chinese Herbal - therapeutic use Lipopolysaccharide Lipopolysaccharides - toxicity Lung - drug effects Lung - pathology Macrophages - drug effects Male MAPKs Medical Education Mice Mice, Inbred BALB C Mitogen-Activated Protein Kinase Kinases - metabolism NF-kappa B - metabolism NF-κB Pulmonary/Respiratory Signal Transduction - drug effects Tenuigenin Time Factors
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