The Broad Substrate Chlorobenzene Dioxygenase and cis-Chlorobenzene Dihydrodiol Dehydrogenase of Pseudomonas sp. Strain P51 Are Linked Evolutionarily to the Enzymes for Benzene and Toluene Degradation (∗)

The chlorobenzene degradation pathway of Pseudomonas sp. strain P51 is an evolutionary novelty. The first enzymes of the pathway, the chlorobenzene dioxygenase and the cis-chlorobenzene dihydrodiol dehydrogenase, are encoded on a plasmid-located transposon Tn5280. Chlorobenzene dioxygenase is a four...

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Veröffentlicht in:	The Journal of biological chemistry 1996-02, Vol.271 (8), p.4009-4016
Hauptverfasser:	Werlen, Christoph, Kohler, Hans-Peter E., van der Meer, Jan Roelof
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Base Sequence Benzene - metabolism Biological Evolution Biotransformation Cloning, Molecular Dioxygenases Gene Transfer, Horizontal Genes, Bacterial Macromolecular Substances Molecular Sequence Data Multigene Family Oxidoreductases - genetics Oxidoreductases - metabolism Oxygenases - genetics Oxygenases - metabolism Phylogeny Pseudomonas Pseudomonas - enzymology Pseudomonas - genetics Recombinant Proteins - metabolism Restriction Mapping Sequence Homology, Amino Acid Substrate Specificity Toluene - metabolism
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