N-glycanase treatment of F(ab') sub(2) derived from asymmetric murine IgG sub(3) mAb determines the acquisition of precipitating activity

The aim of this study was to analyse four anti-DNP asymmetrically glycosylated monoclonal IgG3 antibodies (194/2, 194/5, 194/6 and 194/12) before and after carbohydrate manipulation. Microheterogeneity in the composition of the carbohydrate moiety involved in Fab' glycosylation was detected usi...

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Veröffentlicht in:Molecular immunology 1995-01, Vol.32 (14-15), p.1123-1130
Hauptverfasser: Mathov, I, Plotkin, LI, Squiquera, L, Fossati, CA, Margni, R A, Leoni, J
Format: Artikel
Sprache:eng
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