Dermal expression of laminin-332 and type IV collagen in humans with severe sepsis

Background An intact basement membrane at the dermal–epidermal junction is essential to the viability of the skin. The effect of sepsis on the basement membrane is unknown. Methods Skin biopsies were used to study basement membrane structure in severe sepsis (Day 1). Subsequent biopsies were taken o...

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Veröffentlicht in:	Acta anaesthesiologica Scandinavica 2015-09, Vol.59 (8), p.1009-1014
Hauptverfasser:	Koskela, M., Gäddnäs, F., Koivukangas, V., Oikarinen, A., Laurila, J., Kallioinen, M., Ala-Kokko, T. I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Basement Membrane - metabolism Collagen Type IV - metabolism Female Follow-Up Studies Humans Immunohistochemistry Laminin - metabolism Male Middle Aged Sepsis - metabolism Skin - metabolism
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