Sputum high mobility group box-1 in asthmatic children: a noninvasive sensitive biomarker reflecting disease status

Abstract Background The monitoring of asthma is based mainly on clinical history, physical examination, and lung function test evaluation. To improve knowledge of the disease, new biomarkers of airway inflammation, including high mobility group box-1 (HMGB1), are being developed. Objective To evalua...

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Veröffentlicht in:	Annals of allergy, asthma, & immunology asthma, & immunology, 2015-08, Vol.115 (2), p.103-107
Hauptverfasser:	Cuppari, Caterina, MD, Manti, Sara, MD, Chirico, Valeria, MD, Caruso, Rosangela, MD, Salpietro, Vincenzo, MD, Giacchi, Valentina, MD, Laganà, Francesca, MD, Arrigo, Teresa, MD, Salpietro, Carmelo, MD, Leonardi, Salvatore, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Allergy and Immunology Asthma - diagnosis Asthma - genetics Asthma - immunology Asthma - pathology Biomarkers - metabolism Case-Control Studies Child Cohort Studies Female Gene Expression HMGB1 Protein - genetics HMGB1 Protein - metabolism Humans Immunoglobulin E - genetics Lung - immunology Lung - metabolism Lung - pathology Male Respiratory Function Tests Severity of Illness Index Sputum - chemistry
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