In vivo sequence diversity of the protease of human immunodeficiency virus type 1: presence of protease inhibitor-resistant variants in untreated subjects
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Veröffentlicht in: | Journal of Virology 1996-03, Vol.70 (3), p.2038-2043 |
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container_title | Journal of Virology |
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creator | Lech, W J Wang, G Yang, Y L Chee, Y Dorman, K McCrae, D Lazzeroni, L C Erickson, J W Sinsheimer, J S Kaplan, A H |
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doi_str_mv | 10.1128/jvi.70.3.2038-2043.1996 |
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</description><identifier>ISSN: 0022-538X</identifier><identifier>EISSN: 1098-5514</identifier><identifier>DOI: 10.1128/jvi.70.3.2038-2043.1996</identifier><identifier>PMID: 8627733</identifier><language>eng</language><publisher>United States: American Society for Microbiology</publisher><subject>AIDS/HIV ; Amino Acid Sequence ; Antiviral Agents - pharmacology ; Base Sequence ; DNA, Viral ; Drug Resistance, Microbial ; Genetic Variation ; HIV Infections - blood ; HIV Infections - virology ; HIV Protease - genetics ; HIV Protease Inhibitors - pharmacology ; HIV-1 - drug effects ; HIV-1 - enzymology ; HIV-1 - genetics ; human immunodeficiency virus 1 ; Humans ; Molecular Sequence Data ; Substrate Specificity ; Zidovudine - pharmacology</subject><ispartof>Journal of Virology, 1996-03, Vol.70 (3), p.2038-2043</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c588t-d3d630d8ee0f6c6ca498c2683b8f6243c88e7d3bc3fad74448ebc9d81d1fc3423</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC190036/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC190036/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,315,728,781,785,886,27929,27930,53796,53798</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8627733$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lech, W J</creatorcontrib><creatorcontrib>Wang, G</creatorcontrib><creatorcontrib>Yang, Y L</creatorcontrib><creatorcontrib>Chee, Y</creatorcontrib><creatorcontrib>Dorman, K</creatorcontrib><creatorcontrib>McCrae, D</creatorcontrib><creatorcontrib>Lazzeroni, L C</creatorcontrib><creatorcontrib>Erickson, J W</creatorcontrib><creatorcontrib>Sinsheimer, J S</creatorcontrib><creatorcontrib>Kaplan, A H</creatorcontrib><title>In vivo sequence diversity of the protease of human immunodeficiency virus type 1: presence of protease inhibitor-resistant variants in untreated subjects</title><title>Journal of Virology</title><addtitle>J Virol</addtitle><description>Article Usage Stats
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</description><subject>AIDS/HIV</subject><subject>Amino Acid Sequence</subject><subject>Antiviral Agents - pharmacology</subject><subject>Base Sequence</subject><subject>DNA, Viral</subject><subject>Drug Resistance, Microbial</subject><subject>Genetic Variation</subject><subject>HIV Infections - blood</subject><subject>HIV Infections - virology</subject><subject>HIV Protease - genetics</subject><subject>HIV Protease Inhibitors - pharmacology</subject><subject>HIV-1 - drug effects</subject><subject>HIV-1 - enzymology</subject><subject>HIV-1 - genetics</subject><subject>human immunodeficiency virus 1</subject><subject>Humans</subject><subject>Molecular Sequence Data</subject><subject>Substrate Specificity</subject><subject>Zidovudine - pharmacology</subject><issn>0022-538X</issn><issn>1098-5514</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkcuKFDEUhgtRxnb0EcS4cVdtbpWkBBcyeBkYcKPgLqSSU1NpuiptkirpV_FpTdlN46xcHcJ_vp8kX1W9InhLCFVvd4vfSrxlW4qZqinmbEvaVjyqNgS3qm4awh9XG4wprRumfjytnqW0w5hwLvhVdaUElZKxTfX7dkKLXwJK8HOGyQJyfoGYfD6i0KM8ADrEkMEkWM_DPJoJ-XGcp-Cg99YX5lga4pxQPh4AkXcFgPS3qgAX2E-D73wOsS6pT9lMGS0m-jJTCdE85Qgmg0Np7nZgc3pePenNPsGL87yuvn_6-O3mS3339fPtzYe72jZK5doxJxh2CgD3wgpreKssFYp1qheUM6sUSMc6y3rjJOdcQWdbp4gjvWWcsuvq_an3MHcjOAvlJmavD9GPJh51MF4_TCY_6PuwaNJizETh35z5GMofpqxHnyzs92aCMCctZREjm_a_i0Ri2oiGlUV5WrQxpBShv1yGYL3q10W_llgzverXq3696i_ky3_fcuHOvkv--pQP_n745SNok8aHbewPueO-RQ</recordid><startdate>19960301</startdate><enddate>19960301</enddate><creator>Lech, W J</creator><creator>Wang, G</creator><creator>Yang, Y L</creator><creator>Chee, Y</creator><creator>Dorman, K</creator><creator>McCrae, D</creator><creator>Lazzeroni, L C</creator><creator>Erickson, J W</creator><creator>Sinsheimer, J S</creator><creator>Kaplan, A H</creator><general>American Society for Microbiology</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19960301</creationdate><title>In vivo sequence diversity of the protease of human immunodeficiency virus type 1: presence of protease inhibitor-resistant variants in untreated subjects</title><author>Lech, W J ; 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</abstract><cop>United States</cop><pub>American Society for Microbiology</pub><pmid>8627733</pmid><doi>10.1128/jvi.70.3.2038-2043.1996</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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subjects | AIDS/HIV Amino Acid Sequence Antiviral Agents - pharmacology Base Sequence DNA, Viral Drug Resistance, Microbial Genetic Variation HIV Infections - blood HIV Infections - virology HIV Protease - genetics HIV Protease Inhibitors - pharmacology HIV-1 - drug effects HIV-1 - enzymology HIV-1 - genetics human immunodeficiency virus 1 Humans Molecular Sequence Data Substrate Specificity Zidovudine - pharmacology |
title | In vivo sequence diversity of the protease of human immunodeficiency virus type 1: presence of protease inhibitor-resistant variants in untreated subjects |
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