Hypothalamic ER stress: A bridge between leptin resistance and obesity

The prevalence of obesity has increased worldwide at an alarming rate. However, non-invasive pharmacological treatments remain elusive. Leptin resistance is a general feature of obesity, thus strategies aimed at enhancing the sensitivity to this hormone may constitute an excellent therapeutical appr...

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Veröffentlicht in:	FEBS letters 2015-06, Vol.589 (14), p.1678-1687
Hauptverfasser:	Ramírez, Sara, Claret, Marc
Format:	Artikel
Sprache:	eng
Schlagworte:	Endoplasmic Reticulum - metabolism ER stress Humans Hypothalamus Hypothalamus - metabolism Leptin - metabolism Leptin resistance Obesity - metabolism POMC neurons
Online-Zugang:	Volltext
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