Comparison of diagnostic test performance in a population of high risk young adults versus a general population presenting with influenza

Highlights • Viral culture performs better in younger than older adults. • The sensitivity of viral culture, EIA and PCR was higher in those infected with influenza A than in those infected with influenza B. • The sensitivity of viral culture was significantly higher in (H1N1)pdm09 subtype cases tha...

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Veröffentlicht in:	Journal of clinical virology 2015-07, Vol.68, p.49-52
Hauptverfasser:	Scheuller, H. Samuel, Lott, Lisa, Haas, Roy, Tavish, Michele, Danaher, Patrick
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Basic military trainee Diagnostic Tests, Routine - methods Enzyme immunoassay (EIA) Female Humans Immunoenzyme Techniques - methods Infectious Disease Influenza Influenza, Human - diagnosis Male Military Personnel Orthomyxoviridae - genetics Orthomyxoviridae - growth & development Orthomyxoviridae - immunology Orthomyxoviridae - isolation & purification Polymerase chain reaction (PCR) Polymerase Chain Reaction - methods Prospective Studies Sensitivity and Specificity Viral culture Virus Cultivation - methods Young Adult
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Zusammenfassung:	Highlights • Viral culture performs better in younger than older adults. • The sensitivity of viral culture, EIA and PCR was higher in those infected with influenza A than in those infected with influenza B. • The sensitivity of viral culture was significantly higher in (H1N1)pdm09 subtype cases than other subtypes.
ISSN:	1386-6532 1873-5967
DOI:	10.1016/j.jcv.2015.04.020