Distinct kinetics and pathways of apoptosis in influenza A and B virus infection

•Differences in apoptosis kinetics of Influenza A and B cell infection were observed.•Both influenza A and B infection activate the PI3K/Akt survival pathway.•IκB/NF-κB survival pathway acts as major contributor for the differences observed. Annual influenza epidemics are associated with high incide...

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Veröffentlicht in:	Virus research 2015-07, Vol.205, p.33-40
Hauptverfasser:	Santos, Luis A, Solá, Susana, Rodrigues, Cecilia MP, Rebelo-de-Andrade, Helena
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Humans Influenza A and B Influenza A virus Influenza A virus - physiology Influenza B virus - physiology Influenza, Human - genetics Influenza, Human - metabolism Influenza, Human - physiopathology Influenza, Human - virology IκB/NF-κB pathway Kinetics NF-kappa B - genetics NF-kappa B - metabolism PI3K/Akt pathway Signal Transduction Virus Replication
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