Copper-Mediated and Copper-Catalyzed Cross-Coupling of Indoles and 1,3-Azoles: Double CH Activation

A new bronze age: The described copper‐mediated cross‐coupling with double CH activation can provide a convergent access to indole‐containing biheteroaryls that are of high interest in pharmaceutical and medicinal chemistry. In this strategy an easily attachable and detachable 2‐pyrimidyl directing...

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Veröffentlicht in:	Angewandte Chemie International Edition 2012-07, Vol.51 (28), p.6993-6997
Hauptverfasser:	Nishino, Mayuko, Hirano, Koji, Satoh, Tetsuya, Miura, Masahiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Activation Age Atmospherics Azoles - chemistry Benzoxazoles - chemistry Bronzes Carbon - chemistry Catalysis Catalysts Copper Copper - pharmacology cross-coupling CH activation Detaching indoles Indoles - chemistry Molecular Structure Oxidants - pharmacology Oxidative Coupling Oxygen - chemistry Strategy synthetic methods
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