Consequences of Cooperativity in Racemizing Supramolecular Systems
Saluting the sergeant: Phg‐BTA (see scheme) cooperatively self‐assembles into helical aggregates and shows unprecedented racemization behavior in the presence of base. In thermodynamically controlled conditions, the addition of a small amount of chiral auxiliary to this mixture results in a deracemi...
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| Veröffentlicht in: | Angewandte Chemie International Edition 2012-06, Vol.51 (26), p.6426-6431 |
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| container_issue | 26 |
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| container_title | Angewandte Chemie International Edition |
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| creator | Cantekin, Seda ten Eikelder, Huub M. M. Markvoort, Albert J. Veld, Martijn A. J. Korevaar, Peter A. Green, Mark M. Palmans, Anja R. A. Meijer, E. W. |
| description | Saluting the sergeant: Phg‐BTA (see scheme) cooperatively self‐assembles into helical aggregates and shows unprecedented racemization behavior in the presence of base. In thermodynamically controlled conditions, the addition of a small amount of chiral auxiliary to this mixture results in a deracemization reaction and a final enantiomeric excess of 32 %. A theoretical model is presented to understand in detail the results obtained. |
| doi_str_mv | 10.1002/anie.201201701 |
| format | Article |
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| subjects | Aggregates deracemization enantiomeric excess Helical Isomerism Molecular Structure nonlinear effects Polymers - chemistry Racemization self-assembly supramolecular chemistry |
| title | Consequences of Cooperativity in Racemizing Supramolecular Systems |
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