Interaction with the Surrounding Water Plays a Key Role in Determining the Aggregation Propensity of Proteins

Understanding the molecular determinants of the relative propensities of proteins to aggregate in a cellular environment is a central issue for treating protein‐aggregation diseases and developing peptide‐based therapeutics. Despite the expectation that protein aggregation can largely be attributed...

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Veröffentlicht in:Angewandte Chemie International Edition 2014-04, Vol.53 (15), p.3961-3964
Hauptverfasser: Chong, Song-Ho, Ham, Sihyun
Format: Artikel
Sprache:eng
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