Progress towards Bioorthogonal Catalysis with Organometallic Compounds

The catalysis of bioorthogonal transformations inside living organisms is a formidable challenge—yet bears great potential for future applications in chemical biology and medicinal chemistry. We herein disclose highly active organometallic ruthenium complexes for bioorthogonal catalysis under biolog...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Angewandte Chemie International Edition 2014-09, Vol.53 (39), p.10536-10540
Hauptverfasser:	Völker, Timo, Dempwolff, Felix, Graumann, Peter L., Meggers, Eric
Format:	Artikel
Sprache:	eng
Schlagworte:	Amines Amines - chemistry Apoptosis - drug effects bioorthogonality Carbamates - chemistry Catalysis Catalysts Cellular Coordination Complexes - chemical synthesis Coordination Complexes - chemistry Coordination Complexes - toxicity Cytoplasm Cytoplasm - chemistry Cytoplasm - metabolism Drugs Fluorescence Fluorescent Dyes - chemistry HeLa Cells homogeneous catalysis Humans Metalorganic compounds Organometallic Compounds - chemistry prodrugs Prodrugs - chemical synthesis Prodrugs - chemistry Prodrugs - toxicity Ruthenium Ruthenium - chemistry uncaging
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!