Live-Cell Stimulated Raman Scattering Imaging of Alkyne-Tagged Biomolecules

Alkynes can be metabolically incorporated into biomolecules including nucleic acids, proteins, lipids, and glycans. In addition to the clickable chemical reactivity, alkynes possess a unique Raman scattering within the Raman‐silent region of a cell. Coupling this spectroscopic signature with Raman m...

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Veröffentlicht in:	Angewandte Chemie International Edition 2014-06, Vol.53 (23), p.5827-5831
Hauptverfasser:	Hong, Senlian, Chen, Tao, Zhu, Yuntao, Li, Ang, Huang, Yanyi, Chen, Xing
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkynes Alkynes - chemistry Biomolecules bioorthogonality Coupling (molecular) Diagnostic Imaging - instrumentation Fluorescence Imaging Microscopy NMR Nuclear magnetic resonance Raman imaging Raman scattering Signatures Spectroscopy Spectrum Analysis, Raman - methods stimulated Raman scattering
Online-Zugang:	Volltext
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