Tacrolimus : a review of its pharmacology, and therapeutic potential in hepatic and renal transplantation

Tacrolimus (FK 506) is a macrolide immunosuppressant which possesses similar but more potent immunosuppressant properties compared with cyclosporin, inhibiting cell-mediated and humoral immune responses. Like cyclosporin, tacrolimus demonstrates considerable interindividual variation in its pharmaco...

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Veröffentlicht in:	Drugs (New York, N.Y.) N.Y.), 1993-10, Vol.46 (4), p.746-794
Hauptverfasser:	PETERS, D. H, FITTON, A, PLOSKER, G. L, FAULDS, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Child, Preschool Humans Immunomodulators Kidney Transplantation Liver Transplantation Medical sciences Pharmacology. Drug treatments Postoperative Complications - drug therapy Tacrolimus - adverse effects Tacrolimus - pharmacokinetics Tacrolimus - pharmacology Tacrolimus - therapeutic use Treatment Outcome
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