ISSLS Prize Winner: Dynamic Loading–Induced Convective Transport Enhances Intervertebral Disc Nutrition

STUDY DESIGN.Experimental animal study of convective transport in the intervertebral disc. OBJECTIVE.To quantify the effects of mechanical loading rate on net transport into the healthy and degenerative intervertebral disc in vivo. SUMMARY OF BACKGROUND DATA.Intervertebral disc degeneration is linke...

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Veröffentlicht in:	Spine (Philadelphia, Pa. 1976) Pa. 1976), 2015-08, Vol.40 (15), p.1158-1164
Hauptverfasser:	Gullbrand, Sarah E, Peterson, Joshua, Ahlborn, Jenna, Mastropolo, Rosemarie, Fricker, Arun, Roberts, Timothy T, Abousayed, Mostafa, Lawrence, James P, Glennon, Joseph C, Ledet, Eric H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Transport - physiology Contrast Media - pharmacokinetics Convection Diffusion Gadolinium DTPA - pharmacokinetics Intervertebral Disc - metabolism Intervertebral Disc Degeneration - metabolism Intervertebral Disc Degeneration - pathology Magnetic Resonance Imaging Rabbits Weight-Bearing - physiology
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