99mTc-Tilmanocept: A Novel Molecular Agent for Lymphatic Mapping and Sentinel Lymph Node Localization
Preoperative lymphatic mapping in conjunction with intraoperative γ-probe detection is widely used for sentinel node localization in melanoma, breast cancer, and other malignancies. (99m)Tc-radiocolloids have been the standard radiotracers used for sentinel node mapping. (99m)Tc-tilmanocept is a rec...
Gespeichert in:
| Veröffentlicht in: | Journal of nuclear medicine technology 2015-06, Vol.43 (2), p.87-91 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 91 |
|---|---|
| container_issue | 2 |
| container_start_page | 87 |
| container_title | Journal of nuclear medicine technology |
| container_volume | 43 |
| creator | Surasi, Devaki Shilpa O'Malley, Janis Bhambhvani, Pradeep |
| description | Preoperative lymphatic mapping in conjunction with intraoperative γ-probe detection is widely used for sentinel node localization in melanoma, breast cancer, and other malignancies. (99m)Tc-radiocolloids have been the standard radiotracers used for sentinel node mapping. (99m)Tc-tilmanocept is a receptor-binding molecular imaging agent approved by the U.S. Food and Drug Administration for lymphatic mapping and lymph node localization in breast cancer, melanoma, clinically node-negative squamous cell carcinoma of the oral cavity, and other solid tumors. It has several advantages over conventional radiocolloids, including rapid injection site clearance, high sentinel node extraction, and low distal node accumulation, which can lead to efficient resource use. |
| doi_str_mv | 10.2967/jnmt.115.155960 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1700682690</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1700682690</sourcerecordid><originalsourceid>FETCH-LOGICAL-c1830-1ebe848100ba98ef138a05bcc40dd24dfa64580f7d23a80d3a796ce788f2c44d3</originalsourceid><addsrcrecordid>eNo9kD1PwzAYhC0EoqUwsyGPLGlfx7Fjs1UVX1ILA2WOHNspqZw4xAlS-fWktDDdcM_d8CB0TWAaS57OtnXVTQlhU8KY5HCCxoRRFjGeslM0BpAkSiThI3QRwhaAsBjEORrFTDLOJR0jK2W11tG6dJWqvbZNd4fn-MV_WYdX3lndO9Xi-cbWHS58i5e7qvlQXanxSjVNWW-wqg1-G-qyHia_9TA3Fi-9Vq78HlhfX6KzQrlgr445Qe8P9-vFU7R8fXxezJeRJoJCRGxuRSIIQK6ksAWhQgHLtU7AmDgxheIJE1CkJqZKgKEqlVzbVIgi1kli6ATdHn6b1n_2NnRZVQZtnVO19X3ISArARcwlDOjsgOrWh9DaImvaslLtLiOQ7d1me7fZ4DY7uB0WN8fzPq-s-ef_ZNIfmSB1gw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1700682690</pqid></control><display><type>article</type><title>99mTc-Tilmanocept: A Novel Molecular Agent for Lymphatic Mapping and Sentinel Lymph Node Localization</title><source>MEDLINE</source><source>EZB-FREE-00999 freely available EZB journals</source><source>Alma/SFX Local Collection</source><creator>Surasi, Devaki Shilpa ; O'Malley, Janis ; Bhambhvani, Pradeep</creator><creatorcontrib>Surasi, Devaki Shilpa ; O'Malley, Janis ; Bhambhvani, Pradeep</creatorcontrib><description>Preoperative lymphatic mapping in conjunction with intraoperative γ-probe detection is widely used for sentinel node localization in melanoma, breast cancer, and other malignancies. (99m)Tc-radiocolloids have been the standard radiotracers used for sentinel node mapping. (99m)Tc-tilmanocept is a receptor-binding molecular imaging agent approved by the U.S. Food and Drug Administration for lymphatic mapping and lymph node localization in breast cancer, melanoma, clinically node-negative squamous cell carcinoma of the oral cavity, and other solid tumors. It has several advantages over conventional radiocolloids, including rapid injection site clearance, high sentinel node extraction, and low distal node accumulation, which can lead to efficient resource use.</description><identifier>ISSN: 0091-4916</identifier><identifier>EISSN: 1535-5675</identifier><identifier>DOI: 10.2967/jnmt.115.155960</identifier><identifier>PMID: 25956693</identifier><language>eng</language><publisher>United States</publisher><subject>Animals ; Carcinoma, Squamous Cell - diagnosis ; Dextrans ; Humans ; Mannans ; Mouth Neoplasms - diagnosis ; Radioactive Tracers ; Sentinel Lymph Node Biopsy - economics ; Sentinel Lymph Node Biopsy - methods ; Technetium Tc 99m Pentetate - analogs & derivatives</subject><ispartof>Journal of nuclear medicine technology, 2015-06, Vol.43 (2), p.87-91</ispartof><rights>2015 by the Society of Nuclear Medicine and Molecular Imaging, Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c1830-1ebe848100ba98ef138a05bcc40dd24dfa64580f7d23a80d3a796ce788f2c44d3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25956693$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Surasi, Devaki Shilpa</creatorcontrib><creatorcontrib>O'Malley, Janis</creatorcontrib><creatorcontrib>Bhambhvani, Pradeep</creatorcontrib><title>99mTc-Tilmanocept: A Novel Molecular Agent for Lymphatic Mapping and Sentinel Lymph Node Localization</title><title>Journal of nuclear medicine technology</title><addtitle>J Nucl Med Technol</addtitle><description>Preoperative lymphatic mapping in conjunction with intraoperative γ-probe detection is widely used for sentinel node localization in melanoma, breast cancer, and other malignancies. (99m)Tc-radiocolloids have been the standard radiotracers used for sentinel node mapping. (99m)Tc-tilmanocept is a receptor-binding molecular imaging agent approved by the U.S. Food and Drug Administration for lymphatic mapping and lymph node localization in breast cancer, melanoma, clinically node-negative squamous cell carcinoma of the oral cavity, and other solid tumors. It has several advantages over conventional radiocolloids, including rapid injection site clearance, high sentinel node extraction, and low distal node accumulation, which can lead to efficient resource use.</description><subject>Animals</subject><subject>Carcinoma, Squamous Cell - diagnosis</subject><subject>Dextrans</subject><subject>Humans</subject><subject>Mannans</subject><subject>Mouth Neoplasms - diagnosis</subject><subject>Radioactive Tracers</subject><subject>Sentinel Lymph Node Biopsy - economics</subject><subject>Sentinel Lymph Node Biopsy - methods</subject><subject>Technetium Tc 99m Pentetate - analogs & derivatives</subject><issn>0091-4916</issn><issn>1535-5675</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kD1PwzAYhC0EoqUwsyGPLGlfx7Fjs1UVX1ILA2WOHNspqZw4xAlS-fWktDDdcM_d8CB0TWAaS57OtnXVTQlhU8KY5HCCxoRRFjGeslM0BpAkSiThI3QRwhaAsBjEORrFTDLOJR0jK2W11tG6dJWqvbZNd4fn-MV_WYdX3lndO9Xi-cbWHS58i5e7qvlQXanxSjVNWW-wqg1-G-qyHia_9TA3Fi-9Vq78HlhfX6KzQrlgr445Qe8P9-vFU7R8fXxezJeRJoJCRGxuRSIIQK6ksAWhQgHLtU7AmDgxheIJE1CkJqZKgKEqlVzbVIgi1kli6ATdHn6b1n_2NnRZVQZtnVO19X3ISArARcwlDOjsgOrWh9DaImvaslLtLiOQ7d1me7fZ4DY7uB0WN8fzPq-s-ef_ZNIfmSB1gw</recordid><startdate>201506</startdate><enddate>201506</enddate><creator>Surasi, Devaki Shilpa</creator><creator>O'Malley, Janis</creator><creator>Bhambhvani, Pradeep</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201506</creationdate><title>99mTc-Tilmanocept: A Novel Molecular Agent for Lymphatic Mapping and Sentinel Lymph Node Localization</title><author>Surasi, Devaki Shilpa ; O'Malley, Janis ; Bhambhvani, Pradeep</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1830-1ebe848100ba98ef138a05bcc40dd24dfa64580f7d23a80d3a796ce788f2c44d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Animals</topic><topic>Carcinoma, Squamous Cell - diagnosis</topic><topic>Dextrans</topic><topic>Humans</topic><topic>Mannans</topic><topic>Mouth Neoplasms - diagnosis</topic><topic>Radioactive Tracers</topic><topic>Sentinel Lymph Node Biopsy - economics</topic><topic>Sentinel Lymph Node Biopsy - methods</topic><topic>Technetium Tc 99m Pentetate - analogs & derivatives</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Surasi, Devaki Shilpa</creatorcontrib><creatorcontrib>O'Malley, Janis</creatorcontrib><creatorcontrib>Bhambhvani, Pradeep</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of nuclear medicine technology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Surasi, Devaki Shilpa</au><au>O'Malley, Janis</au><au>Bhambhvani, Pradeep</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>99mTc-Tilmanocept: A Novel Molecular Agent for Lymphatic Mapping and Sentinel Lymph Node Localization</atitle><jtitle>Journal of nuclear medicine technology</jtitle><addtitle>J Nucl Med Technol</addtitle><date>2015-06</date><risdate>2015</risdate><volume>43</volume><issue>2</issue><spage>87</spage><epage>91</epage><pages>87-91</pages><issn>0091-4916</issn><eissn>1535-5675</eissn><abstract>Preoperative lymphatic mapping in conjunction with intraoperative γ-probe detection is widely used for sentinel node localization in melanoma, breast cancer, and other malignancies. (99m)Tc-radiocolloids have been the standard radiotracers used for sentinel node mapping. (99m)Tc-tilmanocept is a receptor-binding molecular imaging agent approved by the U.S. Food and Drug Administration for lymphatic mapping and lymph node localization in breast cancer, melanoma, clinically node-negative squamous cell carcinoma of the oral cavity, and other solid tumors. It has several advantages over conventional radiocolloids, including rapid injection site clearance, high sentinel node extraction, and low distal node accumulation, which can lead to efficient resource use.</abstract><cop>United States</cop><pmid>25956693</pmid><doi>10.2967/jnmt.115.155960</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0091-4916 |
| ispartof | Journal of nuclear medicine technology, 2015-06, Vol.43 (2), p.87-91 |
| issn | 0091-4916 1535-5675 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1700682690 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Animals Carcinoma, Squamous Cell - diagnosis Dextrans Humans Mannans Mouth Neoplasms - diagnosis Radioactive Tracers Sentinel Lymph Node Biopsy - economics Sentinel Lymph Node Biopsy - methods Technetium Tc 99m Pentetate - analogs & derivatives |
| title | 99mTc-Tilmanocept: A Novel Molecular Agent for Lymphatic Mapping and Sentinel Lymph Node Localization |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-13T00%3A44%3A53IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=99mTc-Tilmanocept:%20A%20Novel%20Molecular%20Agent%20for%20Lymphatic%20Mapping%20and%20Sentinel%20Lymph%20Node%20Localization&rft.jtitle=Journal%20of%20nuclear%20medicine%20technology&rft.au=Surasi,%20Devaki%20Shilpa&rft.date=2015-06&rft.volume=43&rft.issue=2&rft.spage=87&rft.epage=91&rft.pages=87-91&rft.issn=0091-4916&rft.eissn=1535-5675&rft_id=info:doi/10.2967/jnmt.115.155960&rft_dat=%3Cproquest_cross%3E1700682690%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1700682690&rft_id=info:pmid/25956693&rfr_iscdi=true |