Enhancement of HL-60 Differentiation by a New Class of Retinoids with Selective Activity on Retinoid X Receptor (∗)

Cellular responsiveness to retinoic acid and its metabolites is conferred through two distinct families of receptors: the retinoic acid receptors (RARs) and the retinoid X receptors (RXRs). Herein, we report on the identification and characterization of several conformationally restricted retinoids,...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of biological chemistry 1995-12, Vol.270 (51), p.30765-30772
Hauptverfasser:	Apfel, Christian M., Kamber, Markus, Klaus, Michael, Mohr, Peter, Keidel, Siegfried, LeMotte, Peter K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding, Competitive Cell Differentiation - drug effects Cell Differentiation - physiology DNA, Complementary HL-60 Cells Humans Kinetics Molecular Structure Receptors, Retinoic Acid - biosynthesis Receptors, Retinoic Acid - drug effects Receptors, Retinoic Acid - physiology Recombinant Proteins - biosynthesis Recombinant Proteins - drug effects Recombinant Proteins - metabolism Retinoic Acid Receptor alpha Retinoid X Receptors Retinoids - metabolism Retinoids - pharmacology Structure-Activity Relationship Transcription Factors - drug effects Transcription Factors - physiology Transcriptional Activation - drug effects Transfection
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!