Nrf2 up-regulates the induction of acidic sphingomyelinase by electrophiles

Acidic sphingomyelinase (ASMase) catalyses the generation of ceramide from sphingomyelin. Ceramide is a lipid mediator and is implicated in mediating and regulating various cellular processes including cell proliferation, differentiation, stress response and inflammation. We have previously reported...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of biochemistry (Tokyo) 2015-08, Vol.158 (2), p.127-137
Hauptverfasser:	Kumagai, Takeshi, Kozakai, Yosuke, Ishino, Tomohiro, Yajima, Yuichi, Nakagawa, Yasuhito, Imai, Hirotaka
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Cell Line, Tumor Gene Expression Regulation, Neoplastic - drug effects Humans Maleates - pharmacology Molecular Sequence Data NF-E2-Related Factor 2 - metabolism Protein Binding - drug effects Protein Binding - genetics Response Elements - genetics RNA, Messenger - genetics RNA, Messenger - metabolism Sphingomyelin Phosphodiesterase - genetics Sphingomyelin Phosphodiesterase - metabolism Up-Regulation - drug effects Up-Regulation - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!