Role of the cholinergic system in the regulation of neurotrophin synthesis

Nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3) are members of the family of neurotrophins that are highly expressed in the adult hippocampus, and to a lesser extent, in the cerebral cortex and olfactory bulb. Since neuronal expression of neurotrophins i...

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Veröffentlicht in:	Brain research 1995-12, Vol.705 (1), p.247-254
Hauptverfasser:	Yu, Juan, Pizzo, Donald P., Hutton, Leslie A., Perez-Polo, J. Regino
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - pharmacology Biochemistry and metabolism Biological and medical sciences Brain-Derived Neurotrophic Factor - biosynthesis Brain-Derived Neurotrophic Factor - drug effects Brain-Derived Neurotrophic Factor - genetics Central nervous system Cerebellum - cytology Cerebellum - metabolism Cerebral Cortex - cytology Cerebral Cortex - metabolism Cholinergic Agents - pharmacology Cholinergic basal forebrain neuron Cholinergic Fibers - physiology Corpus Striatum - cytology Corpus Striatum - metabolism Fundamental and applied biological sciences. Psychology Gene Expression Regulation - drug effects Hippocampus - cytology Hippocampus - metabolism Immunolesion Immunotoxins - pharmacology Injections, Intraventricular Male mRNA expression N-Glycosyl Hydrolases Nerve Growth Factors - biosynthesis Nerve Growth Factors - drug effects Nerve Growth Factors - genetics Nerve Tissue Proteins - biosynthesis Nerve Tissue Proteins - drug effects Nerve Tissue Proteins - genetics Neurons - metabolism Neurotrophin Neurotrophin 3 Olfactory Bulb - cytology Olfactory Bulb - metabolism Proto-Oncogene Proteins - genetics Rats Rats, Sprague-Dawley Receptor Protein-Tyrosine Kinases - genetics Receptor, trkA Receptors, Cholinergic - metabolism Receptors, Nerve Growth Factor - genetics Ribonucleases Ribosome Inactivating Proteins, Type 1 RNA, Messenger - analysis Saporins Sensitivity and Specificity Septal Nuclei - cytology Septal Nuclei - metabolism Vertebrates: nervous system and sense organs
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