Effects of dietary phenethyl isothiocyanate, ellagic acid, sulindac and calcium on the induction and progression of N-nitrosomethylbenzylamine-induced esophageal carcinogenesis in rats

The potential inhibitory effects of phenethyl isothiocyanate (PEITC), ellagic acid (EA), sulindac and supplemental dietary calcium (SDC) on N-nitrosomethylbenzylamine (NMBA)-induced esophageal carcinogenesis were evaluated in rats utilizing an abbreviated (5 week) NMBA treatment protocol which allow...

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Veröffentlicht in:	Carcinogenesis (New York) 1995-05, Vol.16 (5), p.1101-1106
Hauptverfasser:	Siglin, Joseph C., Brach, David H., Stoner, Gary D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal tumors. Experimental tumors Animals Anticarcinogenic Agents - administration & dosage Anticarcinogenic Agents - pharmacology Biological and medical sciences Body Weight - drug effects Calcium - administration & dosage Calcium - pharmacology Carcinogens - toxicity Diet Dimethylnitrosamine - analogs & derivatives Dimethylnitrosamine - toxicity Ellagic Acid - administration & dosage Ellagic Acid - pharmacology Esophageal Neoplasms - chemically induced Esophageal Neoplasms - pathology Esophageal Neoplasms - prevention & control Experimental digestive system and abdominal tumors Isothiocyanates - administration & dosage Isothiocyanates - pharmacology Male Medical sciences Rats Rats, Inbred F344 Sulindac - administration & dosage Sulindac - pharmacology Time Factors Tumors
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