New-Onset Asthma after Exposure to the Steam System Additive 2-Diethylaminoethanol: A Descriptive Study
Through a leak in the steam heating system, the anticorrosive agent 2-diethylaminoethanol was released into the air of a large office building. Irritative symptoms were experienced by most of the 2500 employees, and 14 workers developed asthma within 3 months of exposure. This study was undertaken t...
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Veröffentlicht in: | Journal of occupational medicine 1994-06, Vol.36 (6), p.623-626 |
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creator | Gadon, Margaret E. Melius, James M. McDonald, Gerald J. Orgel, David |
description | Through a leak in the steam heating system, the anticorrosive agent 2-diethylaminoethanol was released into the air of a large office building. Irritative symptoms were experienced by most of the 2500 employees, and 14 workers developed asthma within 3 months of exposure. This study was undertaken to review clinical characteristics of these asthmatics. Environmental exposure monitoring data and medical records were reviewed. Seven of 14 cases were defined as "confirmed" and 7 of 14 as "suspect," using the National Institute for Occupational Safety and Health surveillance case definition of occupational asthma. Spirometry was positive in 4 of 14 of the cases and peak flow testing in 10 of 14. Three cases were diagnosed on the basis of work-related symptoms and physical examination alone. The study suggests that acute exposure to the irritating steam additive 2-diethylaminoethanol was a contributing factor in the development of clinical asthma in this population. |
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Irritative symptoms were experienced by most of the 2500 employees, and 14 workers developed asthma within 3 months of exposure. This study was undertaken to review clinical characteristics of these asthmatics. Environmental exposure monitoring data and medical records were reviewed. Seven of 14 cases were defined as "confirmed" and 7 of 14 as "suspect," using the National Institute for Occupational Safety and Health surveillance case definition of occupational asthma. Spirometry was positive in 4 of 14 of the cases and peak flow testing in 10 of 14. Three cases were diagnosed on the basis of work-related symptoms and physical examination alone. The study suggests that acute exposure to the irritating steam additive 2-diethylaminoethanol was a contributing factor in the development of clinical asthma in this population.</description><identifier>ISSN: 0096-1736</identifier><identifier>EISSN: 2332-3795</identifier><identifier>PMID: 8071723</identifier><identifier>CODEN: JJOMDZ</identifier><language>eng</language><publisher>Baltimore, MD: Williams & Wilkins</publisher><subject>Adult ; Air Pollution, Indoor - adverse effects ; Asthma - chemically induced ; Asthma - diagnosis ; Asthma - epidemiology ; Biological and medical sciences ; Chemical and industrial products toxicology. Toxic occupational diseases ; Disease Outbreaks ; Equipment Failure ; Ethanolamines - adverse effects ; Heating - instrumentation ; Humans ; Medical sciences ; Middle Aged ; ORIGINAL ARTICLES ; Spirometry ; Toxicology ; Various organic compounds</subject><ispartof>Journal of occupational medicine, 1994-06, Vol.36 (6), p.623-626</ispartof><rights>Copyright © 1994 American College of Occupational and Environmental Medicine</rights><rights>1994 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4109628$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8071723$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gadon, Margaret E.</creatorcontrib><creatorcontrib>Melius, James M.</creatorcontrib><creatorcontrib>McDonald, Gerald J.</creatorcontrib><creatorcontrib>Orgel, David</creatorcontrib><title>New-Onset Asthma after Exposure to the Steam System Additive 2-Diethylaminoethanol: A Descriptive Study</title><title>Journal of occupational medicine</title><addtitle>J Occup Med</addtitle><description>Through a leak in the steam heating system, the anticorrosive agent 2-diethylaminoethanol was released into the air of a large office building. Irritative symptoms were experienced by most of the 2500 employees, and 14 workers developed asthma within 3 months of exposure. This study was undertaken to review clinical characteristics of these asthmatics. Environmental exposure monitoring data and medical records were reviewed. Seven of 14 cases were defined as "confirmed" and 7 of 14 as "suspect," using the National Institute for Occupational Safety and Health surveillance case definition of occupational asthma. Spirometry was positive in 4 of 14 of the cases and peak flow testing in 10 of 14. Three cases were diagnosed on the basis of work-related symptoms and physical examination alone. The study suggests that acute exposure to the irritating steam additive 2-diethylaminoethanol was a contributing factor in the development of clinical asthma in this population.</description><subject>Adult</subject><subject>Air Pollution, Indoor - adverse effects</subject><subject>Asthma - chemically induced</subject><subject>Asthma - diagnosis</subject><subject>Asthma - epidemiology</subject><subject>Biological and medical sciences</subject><subject>Chemical and industrial products toxicology. Toxic occupational diseases</subject><subject>Disease Outbreaks</subject><subject>Equipment Failure</subject><subject>Ethanolamines - adverse effects</subject><subject>Heating - instrumentation</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>ORIGINAL ARTICLES</subject><subject>Spirometry</subject><subject>Toxicology</subject><subject>Various organic compounds</subject><issn>0096-1736</issn><issn>2332-3795</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkEtLxDAUhYMo4zj6E4QsxF0hj6Zp3Q0z4wPEWYyuS5LeOhn6MknV_nuLFmd1D3wfB-45QXPGOYu4zMQpmhOSJRGVPDlHF94fCBGcxdkMzVIiqWR8jt5f4CvaNh4CXvqwrxVWZQCHN99d63sHOLQ47AHvAqga7wYfoMbLorDBfgJm0dpC2A-Vqm3Tjkk1bXWHl3gN3jjb_Uq70BfDJTorVeXharoL9Ha_eV09Rs_bh6fV8jk6MEZCJLRWAqQoeCELDUrLUnJItU7LOCVagy6pYKY0NCaKjz9QU2idpTKhaWZEyhfo9q-3c-1HDz7ktfUGqko10PY-p5IQGifxKF5PYq9rKPLO2Vq5IZ-WGfnNxJU3qiqdaoz1_1pMx2lZeqw5-NC6IxaEJlJk_AdeZnfu</recordid><startdate>19940601</startdate><enddate>19940601</enddate><creator>Gadon, Margaret E.</creator><creator>Melius, James M.</creator><creator>McDonald, Gerald J.</creator><creator>Orgel, David</creator><general>Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7T2</scope><scope>7U2</scope><scope>7U7</scope><scope>C1K</scope></search><sort><creationdate>19940601</creationdate><title>New-Onset Asthma after Exposure to the Steam System Additive 2-Diethylaminoethanol: A Descriptive Study</title><author>Gadon, Margaret E. ; Melius, James M. ; McDonald, Gerald J. ; Orgel, David</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-j220t-5bba5e75d3d7dbeab7f73e8bb8f480bbebf152cfc140a37171cdbb9876189c583</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Adult</topic><topic>Air Pollution, Indoor - adverse effects</topic><topic>Asthma - chemically induced</topic><topic>Asthma - diagnosis</topic><topic>Asthma - epidemiology</topic><topic>Biological and medical sciences</topic><topic>Chemical and industrial products toxicology. Toxic occupational diseases</topic><topic>Disease Outbreaks</topic><topic>Equipment Failure</topic><topic>Ethanolamines - adverse effects</topic><topic>Heating - instrumentation</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>ORIGINAL ARTICLES</topic><topic>Spirometry</topic><topic>Toxicology</topic><topic>Various organic compounds</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gadon, Margaret E.</creatorcontrib><creatorcontrib>Melius, James M.</creatorcontrib><creatorcontrib>McDonald, Gerald J.</creatorcontrib><creatorcontrib>Orgel, David</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Safety Science and Risk</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Journal of occupational medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gadon, Margaret E.</au><au>Melius, James M.</au><au>McDonald, Gerald J.</au><au>Orgel, David</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>New-Onset Asthma after Exposure to the Steam System Additive 2-Diethylaminoethanol: A Descriptive Study</atitle><jtitle>Journal of occupational medicine</jtitle><addtitle>J Occup Med</addtitle><date>1994-06-01</date><risdate>1994</risdate><volume>36</volume><issue>6</issue><spage>623</spage><epage>626</epage><pages>623-626</pages><issn>0096-1736</issn><eissn>2332-3795</eissn><coden>JJOMDZ</coden><abstract>Through a leak in the steam heating system, the anticorrosive agent 2-diethylaminoethanol was released into the air of a large office building. Irritative symptoms were experienced by most of the 2500 employees, and 14 workers developed asthma within 3 months of exposure. This study was undertaken to review clinical characteristics of these asthmatics. Environmental exposure monitoring data and medical records were reviewed. Seven of 14 cases were defined as "confirmed" and 7 of 14 as "suspect," using the National Institute for Occupational Safety and Health surveillance case definition of occupational asthma. Spirometry was positive in 4 of 14 of the cases and peak flow testing in 10 of 14. Three cases were diagnosed on the basis of work-related symptoms and physical examination alone. The study suggests that acute exposure to the irritating steam additive 2-diethylaminoethanol was a contributing factor in the development of clinical asthma in this population.</abstract><cop>Baltimore, MD</cop><pub>Williams & Wilkins</pub><pmid>8071723</pmid><tpages>4</tpages></addata></record> |
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source | MEDLINE; Journals@Ovid Complete |
subjects | Adult Air Pollution, Indoor - adverse effects Asthma - chemically induced Asthma - diagnosis Asthma - epidemiology Biological and medical sciences Chemical and industrial products toxicology. Toxic occupational diseases Disease Outbreaks Equipment Failure Ethanolamines - adverse effects Heating - instrumentation Humans Medical sciences Middle Aged ORIGINAL ARTICLES Spirometry Toxicology Various organic compounds |
title | New-Onset Asthma after Exposure to the Steam System Additive 2-Diethylaminoethanol: A Descriptive Study |
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