Does neoadjuvant chemotherapy plus cytoreductive surgery improve survival rates in patients with advanced epithelial ovarian cancer compared with cytoreductive surgery alone?

The purpose of this study was to compare the outcomes of interval debulking surgery after neoadjuvant chemotherapy (NAC/IDS) with primary debulking surgery (PDS) in patients diagnosed with advanced epithelial ovarian cancer (EOC). A total of 292 patients with IIIC and IV disease stages, who were tre...

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Veröffentlicht in:	Journal of B.U. ON. 2015-05, Vol.20 (3), p.847-854
Hauptverfasser:	Solmaz, Ulas, Mat, Emre, Dereli, Murat Levent, Turan, Volkan, Peker, Nuri, Tosun, Gokhan, Dogan, Askin, Adiyeke, Mehmet, Ozdemir, Aykut, Gungorduk, Kemal, Sanci, Muzaffer, Yildirim, Yusuf
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Carboplatin - administration & dosage Carcinoma, Ovarian Epithelial Chemotherapy, Adjuvant Cytoreduction Surgical Procedures - adverse effects Cytoreduction Surgical Procedures - mortality Disease-Free Survival Docetaxel Female Humans Kaplan-Meier Estimate Middle Aged Multivariate Analysis Neoadjuvant Therapy - adverse effects Neoadjuvant Therapy - mortality Neoplasm Staging Neoplasms, Glandular and Epithelial - mortality Neoplasms, Glandular and Epithelial - pathology Neoplasms, Glandular and Epithelial - therapy Ovarian Neoplasms - mortality Ovarian Neoplasms - pathology Ovarian Neoplasms - therapy Paclitaxel - administration & dosage Patient Selection Proportional Hazards Models Retrospective Studies Risk Factors Taxoids - administration & dosage Time Factors Treatment Outcome
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