Apoptosis and anergy of T cell induced by pancreatic stellate cells-derived galectin-1 in pancreatic cancer

Galectin-1, a β-galactoside-binding protein implicated in cancer cell immune privilege, was highly expressed in activated pancreatic stellate cells (PSCs). This study was designed to investigate the relationship between PSC-derived galectin-1 and tumor immunity in pancreatic cancer. Isolated PSCs we...

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Veröffentlicht in:	Tumor biology 2015-07, Vol.36 (7), p.5617-5626
Hauptverfasser:	Tang, Dong, Gao, Jun, Wang, Sen, Yuan, Zhongxu, Ye, Nianyuan, Chong, Yang, Xu, Chuanqi, Jiang, Xuetong, Li, Bin, Yin, Wei, Miao, Yi, Wang, Daorong, Jiang, Kuirong
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Apoptosis Apoptosis - genetics Biomedical and Life Sciences Biomedicine Cancer Research Cell Differentiation - genetics Cell Proliferation - genetics Cellular biology Clonal Anergy - genetics Cytokines - biosynthesis Female Galectin 1 - biosynthesis Galectin 1 - genetics Gene Expression Regulation, Neoplastic Humans Male Middle Aged Pancreatic cancer Pancreatic Neoplasms - genetics Pancreatic Neoplasms - immunology Pancreatic Neoplasms - pathology Pancreatic Stellate Cells - pathology Proteins Research Article T-Lymphocytes - immunology T-Lymphocytes - pathology Tumor Microenvironment - genetics
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