Separating depressive comorbidity from panic disorder: A combined functional magnetic resonance imaging and machine learning approach

Abstract Background Depression is frequent in panic disorder (PD); yet, little is known about its influence on the neural substrates of PD. Difficulties in fear inhibition during safety signal processing have been reported as a pathophysiological feature of PD that is attenuated by depression. We in...

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Veröffentlicht in:	Journal of affective disorders 2015-09, Vol.184, p.182-192
Hauptverfasser:	Lueken, Ulrike, Straube, Benjamin, Yang, Yunbo, Hahn, Tim, Beesdo-Baum, Katja, Wittchen, Hans-Ulrich, Konrad, Carsten, Ströhle, Andreas, Wittmann, André, Gerlach, Alexander L, Pfleiderer, Bettina, Arolt, Volker, Kircher, Tilo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Agoraphobia - complications Agoraphobia - psychology Amygdala Comorbidity Conditioning (Psychology) Depression Depressive Disorder - diagnosis Depressive Disorder - pathology Depressive Disorder - psychology Depressive Disorder, Major - complications Depressive Disorder, Major - diagnosis Depressive Disorder, Major - psychology Diagnosis, Differential Diagnostic and Statistical Manual of Mental Disorders Extinction, Psychological Fear - psychology Fear conditioning Female fMRI Humans Machine Learning Magnetic Resonance Imaging Male Neuropsychological Tests Panic disorder Panic Disorder - complications Panic Disorder - diagnosis Panic Disorder - pathology Panic Disorder - psychology Predictive Value of Tests Psychiatry
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