Induction of 15-lipoxygenase by interleukin-13 in human blood monocytes

15-Lipoxygenase (15-LO) catalyzes hydroperoxidation of fatty acids, a reaction of potential relevance to inflammation, membrane remodeling, and atherosclerosis. In human leukocytes, 15-lipoxygenation of arachidonic acid produces 15-(S)-hydroxyeicosatetraenoic acid and lipoxin A4, which suppress whit...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The Journal of biological chemistry 1994-11, Vol.269 (44), p.27631-27634
Hauptverfasser:	Nassar, G M, Morrow, J D, Roberts, L J, Lakkis, F G, Badr, K F
Format:	Artikel
Sprache:	eng
Schlagworte:	Arachidonate 15-Lipoxygenase - biosynthesis Base Sequence DNA Primers - chemistry Gene Expression - drug effects Humans Hydroxyeicosatetraenoic Acids - metabolism In Vitro Techniques Interleukin-10 - pharmacology Interleukin-13 - pharmacology Interleukin-4 - pharmacology Molecular Sequence Data Monocytes - enzymology RNA, Messenger - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!