Antioxidant and antiproliferative activities in different maturation stages of broccoli (Brassica oleracea Italica) biofortified with selenium
•We analyse the potential broccoli enriched with selenium to a functional food.•Broccoli has significant antioxidant and antiproliferative activities.•Biofortification increased the amount of phenolic compounds and antioxidant activity.•The activities studied are influenced by the development of bro...
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Veröffentlicht in: | Food chemistry 2016-01, Vol.190, p.771-776 |
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creator | Bachiega, Patricia Salgado, Jocelem Mastrodi de Carvalho, João Ernesto Ruiz, Ana Lúcia T.G Schwarz, Kélin Tezotto, Tiago Morzelle, Maressa Caldeira |
description | •We analyse the potential broccoli enriched with selenium to a functional food.•Broccoli has significant antioxidant and antiproliferative activities.•Biofortification increased the amount of phenolic compounds and antioxidant activity.•The activities studied are influenced by the development of broccoli.•The broccoli seedlings had higher antioxidant and anti-proliferative activity.
In this work, three different broccoli maturity stages subjected to biofortification with selenium were evaluated for antioxidant and antiproliferative activities. Antioxidant trials have shown that the maturation stages biofortified with selenium had significantly higher amounts of phenolic compounds and antioxidant activity, especially seedlings. Although non-polar extracts of all samples show antiproliferative activity, the extract of broccoli seedlings biofortified with selenium stood out, presenting cytocidal activity for a glioma line (U251, GI50 28.5mgL−1). |
doi_str_mv | 10.1016/j.foodchem.2015.06.024 |
format | Article |
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In this work, three different broccoli maturity stages subjected to biofortification with selenium were evaluated for antioxidant and antiproliferative activities. Antioxidant trials have shown that the maturation stages biofortified with selenium had significantly higher amounts of phenolic compounds and antioxidant activity, especially seedlings. Although non-polar extracts of all samples show antiproliferative activity, the extract of broccoli seedlings biofortified with selenium stood out, presenting cytocidal activity for a glioma line (U251, GI50 28.5mgL−1).</description><identifier>ISSN: 0308-8146</identifier><identifier>EISSN: 1873-7072</identifier><identifier>DOI: 10.1016/j.foodchem.2015.06.024</identifier><identifier>PMID: 26213037</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Antioxidant ; Antioxidants - chemistry ; Antiproliferative ; Brassica - chemistry ; Broccoli ; Glucosinolates ; Phenols ; Selenium - chemistry ; Sodium selenate</subject><ispartof>Food chemistry, 2016-01, Vol.190, p.771-776</ispartof><rights>2015 Elsevier Ltd</rights><rights>Copyright © 2015 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c453t-92b3eb5fe1d4a603dce2e1ca1e941105cb2156e96a6051bf7ae9b2c6efb4183</citedby><cites>FETCH-LOGICAL-c453t-92b3eb5fe1d4a603dce2e1ca1e941105cb2156e96a6051bf7ae9b2c6efb4183</cites><orcidid>0000-0002-6517-5464</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.foodchem.2015.06.024$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26213037$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bachiega, Patricia</creatorcontrib><creatorcontrib>Salgado, Jocelem Mastrodi</creatorcontrib><creatorcontrib>de Carvalho, João Ernesto</creatorcontrib><creatorcontrib>Ruiz, Ana Lúcia T.G</creatorcontrib><creatorcontrib>Schwarz, Kélin</creatorcontrib><creatorcontrib>Tezotto, Tiago</creatorcontrib><creatorcontrib>Morzelle, Maressa Caldeira</creatorcontrib><title>Antioxidant and antiproliferative activities in different maturation stages of broccoli (Brassica oleracea Italica) biofortified with selenium</title><title>Food chemistry</title><addtitle>Food Chem</addtitle><description>•We analyse the potential broccoli enriched with selenium to a functional food.•Broccoli has significant antioxidant and antiproliferative activities.•Biofortification increased the amount of phenolic compounds and antioxidant activity.•The activities studied are influenced by the development of broccoli.•The broccoli seedlings had higher antioxidant and anti-proliferative activity.
In this work, three different broccoli maturity stages subjected to biofortification with selenium were evaluated for antioxidant and antiproliferative activities. Antioxidant trials have shown that the maturation stages biofortified with selenium had significantly higher amounts of phenolic compounds and antioxidant activity, especially seedlings. Although non-polar extracts of all samples show antiproliferative activity, the extract of broccoli seedlings biofortified with selenium stood out, presenting cytocidal activity for a glioma line (U251, GI50 28.5mgL−1).</description><subject>Antioxidant</subject><subject>Antioxidants - chemistry</subject><subject>Antiproliferative</subject><subject>Brassica - chemistry</subject><subject>Broccoli</subject><subject>Glucosinolates</subject><subject>Phenols</subject><subject>Selenium - chemistry</subject><subject>Sodium selenate</subject><issn>0308-8146</issn><issn>1873-7072</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc1O3TAQha2KqlxoXwF5CYuktpM4yY4ftRQJqYt2b_lnXOYqicF2gL4Ez1xfXWDbhTWSz3dmNHMIOeGs5ozLr9vah-DsHcy1YLyrmayZaD-QDR_6pupZLw7IhjVsqAbeykNylNKWMVbY4RM5FFLwhjX9hrxcLBnDMzq9ZKoXV17G-xgm9BB1xkeg2paCGSFRXKhDXxQo9KzzukPCQlPWf4ocPDUxWFvc9PQy6pTQahqm0smCpjdZT-XjjBoMPsSMHsHRJ8x3NMEEC67zZ_LR6ynBl9d6TH59__b76kd1-_P65uritrJt1-RqFKYB03ngrtWSNc6CAG41h7HlnHXWCN5JGGURO258r2E0wkrwpuVDc0xO913Log8rpKxmTBamSS8Q1qS4HMd27Ea5Q-UetTGkFMGr-4izjn8VZ2qXhNqqtyTULgnFpCpJFOPJ64zVzODebW-nL8D5HoCy5yNCVMkiLBYcRrBZuYD_m_EPbzShyg</recordid><startdate>20160101</startdate><enddate>20160101</enddate><creator>Bachiega, Patricia</creator><creator>Salgado, Jocelem Mastrodi</creator><creator>de Carvalho, João Ernesto</creator><creator>Ruiz, Ana Lúcia T.G</creator><creator>Schwarz, Kélin</creator><creator>Tezotto, Tiago</creator><creator>Morzelle, Maressa Caldeira</creator><general>Elsevier Ltd</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-6517-5464</orcidid></search><sort><creationdate>20160101</creationdate><title>Antioxidant and antiproliferative activities in different maturation stages of broccoli (Brassica oleracea Italica) biofortified with selenium</title><author>Bachiega, Patricia ; Salgado, Jocelem Mastrodi ; de Carvalho, João Ernesto ; Ruiz, Ana Lúcia T.G ; Schwarz, Kélin ; Tezotto, Tiago ; Morzelle, Maressa Caldeira</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c453t-92b3eb5fe1d4a603dce2e1ca1e941105cb2156e96a6051bf7ae9b2c6efb4183</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Antioxidant</topic><topic>Antioxidants - chemistry</topic><topic>Antiproliferative</topic><topic>Brassica - chemistry</topic><topic>Broccoli</topic><topic>Glucosinolates</topic><topic>Phenols</topic><topic>Selenium - chemistry</topic><topic>Sodium selenate</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bachiega, Patricia</creatorcontrib><creatorcontrib>Salgado, Jocelem Mastrodi</creatorcontrib><creatorcontrib>de Carvalho, João Ernesto</creatorcontrib><creatorcontrib>Ruiz, Ana Lúcia T.G</creatorcontrib><creatorcontrib>Schwarz, Kélin</creatorcontrib><creatorcontrib>Tezotto, Tiago</creatorcontrib><creatorcontrib>Morzelle, Maressa Caldeira</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Food chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bachiega, Patricia</au><au>Salgado, Jocelem Mastrodi</au><au>de Carvalho, João Ernesto</au><au>Ruiz, Ana Lúcia T.G</au><au>Schwarz, Kélin</au><au>Tezotto, Tiago</au><au>Morzelle, Maressa Caldeira</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antioxidant and antiproliferative activities in different maturation stages of broccoli (Brassica oleracea Italica) biofortified with selenium</atitle><jtitle>Food chemistry</jtitle><addtitle>Food Chem</addtitle><date>2016-01-01</date><risdate>2016</risdate><volume>190</volume><spage>771</spage><epage>776</epage><pages>771-776</pages><issn>0308-8146</issn><eissn>1873-7072</eissn><abstract>•We analyse the potential broccoli enriched with selenium to a functional food.•Broccoli has significant antioxidant and antiproliferative activities.•Biofortification increased the amount of phenolic compounds and antioxidant activity.•The activities studied are influenced by the development of broccoli.•The broccoli seedlings had higher antioxidant and anti-proliferative activity.
In this work, three different broccoli maturity stages subjected to biofortification with selenium were evaluated for antioxidant and antiproliferative activities. Antioxidant trials have shown that the maturation stages biofortified with selenium had significantly higher amounts of phenolic compounds and antioxidant activity, especially seedlings. Although non-polar extracts of all samples show antiproliferative activity, the extract of broccoli seedlings biofortified with selenium stood out, presenting cytocidal activity for a glioma line (U251, GI50 28.5mgL−1).</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>26213037</pmid><doi>10.1016/j.foodchem.2015.06.024</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0002-6517-5464</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Antioxidant Antioxidants - chemistry Antiproliferative Brassica - chemistry Broccoli Glucosinolates Phenols Selenium - chemistry Sodium selenate |
title | Antioxidant and antiproliferative activities in different maturation stages of broccoli (Brassica oleracea Italica) biofortified with selenium |
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