Flavinylation of Monoamine Oxidase B (∗)

Monoamine oxidase B (MAO B) catalyzes the oxidative deamination of biogenic and xenobiotic amines. The oxidative step is coupled to the reduction of an obligatory cofactor, FAD, which is covalently linked to the enzyme at Cys397. In this study, we developed a novel riboflavin-depleted (Rib-) COS-7 c...

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Veröffentlicht in:	The Journal of biological chemistry 1995-10, Vol.270 (40), p.23653-23660
Hauptverfasser:	Zhou, Binhua P., Lewis, Duane A., Kwan, Sau-Wah, Abell, Creed W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoenzymes - genetics Apoenzymes - metabolism Binding Sites Cell Line DNA, Complementary - genetics Flavin-Adenine Dinucleotide - metabolism Flavins - metabolism Glutamic Acid - genetics Glutamic Acid - metabolism In Vitro Techniques Mitochondria - enzymology Monoamine Oxidase - genetics Monoamine Oxidase - metabolism Mutagenesis, Site-Directed
Online-Zugang:	Volltext
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