Hepatic granulomas as primary presentation of Mycobacterium avium infection in an HIV-negative, nonimmunosuppressed patient
Nontuberculous hepatic granuloma in patients not infected by human immunodeficiency virus (HIV) is rare. We report an 89-year-old woman who presented with hepatic granuloma without lung involvement. Ultrasonography and computed tomography (CT) of the abdomen showed low-density lesions in the liver....
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| Veröffentlicht in: | Clinical journal of gastroenterology 2009-12, Vol.2 (6), p.431-437 |
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| container_title | Clinical journal of gastroenterology |
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| creator | Toyoda, Megumi Yokomori, Hiroaki Kaneko, Fumihiko Yoshida, Hide Takahashi, Akihiko Hoshi, Kenta Takeuchi, Hajime Tahara, Kumiko Kondo, Hirobumi Motoori, Tadashi |
| description | Nontuberculous hepatic granuloma in patients not infected by human immunodeficiency virus (HIV) is rare. We report an 89-year-old woman who presented with hepatic granuloma without lung involvement. Ultrasonography and computed tomography (CT) of the abdomen showed low-density lesions in the liver. Histopathological examination of a liver biopsy revealed florid, caseating granulomatous reaction with aggregates of epithelioid histiocytes and Langerhans-type giant cells in a predominantly portal and periportal distribution. Gastric juice cultures were positive for
Mycobacterium avium
. The patient was treated with antimycobacterial therapy. Her clinical condition improved dramatically within 1 month of starting therapy, with marked reduction in hepatomegaly together with normalization of liver biochemistry and CT findings. |
| doi_str_mv | 10.1007/s12328-009-0117-5 |
| format | Article |
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| source | Springer Nature - Complete Springer Journals |
| subjects | Abdominal Surgery Case Report Colorectal Surgery Gastroenterology Hepatology Medicine Medicine & Public Health Surgical Oncology |
| title | Hepatic granulomas as primary presentation of Mycobacterium avium infection in an HIV-negative, nonimmunosuppressed patient |
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