Inflammatory Muscle Diseases

To the Editor: In the review article on inflammatory muscle diseases, Dalakas (April 30 issue) 1 outlines four major subtypes. In 1998, Gherardi et al. described a new but underrecognized clinical variant, called macrophagic myofasciitis, 2 a condition that presents as diffuse myalgias of variable i...

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Veröffentlicht in:The New England journal of medicine 2015-07, Vol.373 (4), p.393-394
Hauptverfasser: Young, Pablo, Finn, Barbara C, Reisin, Ricardo, Chen, Lung-Fang, Chao, Chia-Ter, Chen, Chung-Jen, Dalakas, Marinos C
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container_end_page 394
container_issue 4
container_start_page 393
container_title The New England journal of medicine
container_volume 373
creator Young, Pablo
Finn, Barbara C
Reisin, Ricardo
Chen, Lung-Fang
Chao, Chia-Ter
Chen, Chung-Jen
Dalakas, Marinos C
description To the Editor: In the review article on inflammatory muscle diseases, Dalakas (April 30 issue) 1 outlines four major subtypes. In 1998, Gherardi et al. described a new but underrecognized clinical variant, called macrophagic myofasciitis, 2 a condition that presents as diffuse myalgias of variable intensity associated with chronic fatigue. Myalgia predominantly affects the lower limbs and is often aggravated by exercise. It is associated with arthralgias in 50 to 60% of patients, as well as fever in 30% of patients. 3 Results on electromyography may be myopathic, and creatine kinase levels may be elevated in up to 50% of patients. 4 This disease . . .
doi_str_mv 10.1056/NEJMc1506827
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subjects Aluminum
Creatine
Creatine kinase
Electromyography
Fatigue
Fever
Humans
Muscle, Skeletal - pathology
Myalgia
Myositis
title Inflammatory Muscle Diseases
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