Chondroitin sulfate proteoglycans: Key modulators in the developing and pathologic central nervous system

Chondroitin Sulfate Proteoglycans (CSPGs) are a major component of the extracellular matrix in the central nervous system (CNS) and play critical role in the development and pathophysiology of the brain and spinal cord. Developmentally, CSPGs provide guidance cues for growth cones and contribute to...

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Veröffentlicht in:	Experimental neurology 2015-07, Vol.269, p.169-187
Hauptverfasser:	Dyck, Scott M., Karimi-Abdolrezaee, Soheila
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Axonal regeneration Brain Injuries - drug therapy Central Central Nervous System - drug effects Central Nervous System - metabolism Chondroitin sulfate proteoglycans Chondroitin Sulfate Proteoglycans - metabolism Chondroitin Sulfate Proteoglycans - pharmacology Development Extracellular matrix Glial scar Humans Intacellular mechanisms LAR Multiple sclerosis Nerve Regeneration - drug effects Nerve Regeneration - physiology Nervous system Neuronal Plasticity - drug effects Plasticity PTPσ Spinal Cord Injuries - drug therapy Spinal cord injury
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